Issues

Observing the behaviour of individual biomolecules in action is a powerful approach for probing biological mechanisms. This issue of Essays in Biochemistry showcases different types of single-molecule techniques and their applications to investigate processes that are fundamental to life. This is also the first issue written and edited entirely by early career researchers who help drive this exciting field of research forward. The cover image shows single, newly replicated DNA molecules that have been labelled with a red dye to enable their visualisation by microscopy. The image was provided by Dr Dominika Gruszka.