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Volume 65, Issue 6
November 2021
Essays in Biochemistry Cover Image for Volume 65, Issue 6
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  • Cover Image

    Cover Image

    Issue cover image
    Nuclear receptors are classically defined as ligand-activated transcription factors that regulate key functions in reproduction, development, and physiology. This themed issue on ‘Exploring Nuclear Receptors’ focusses on the broad application of new knowledge in this field for therapy across diverse disease states including cancer, cardiovascular disease, various inflammatory diseases, the aging brain, and COVID-19. Cover image created by Kelly Kage and Daniel Frigo.
ISSN 0071-1365
EISSN 1744-1358
In this Issue

Exploring Nuclear Receptors

Editorial

Nuclear receptors: from molecular mechanisms to therapeutics
Daniel E. Frigo; Maria Bondesson; Cecilia Williams
Essays Biochem (2021) 65 (6): 847–856.
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Review Articles

Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM
Ping Yi; Xinzhe Yu; Zhao Wang; Bert W. O'Malley
Essays Biochem (2021) 65 (6): 857–866.
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The physiological role of estrogen receptor functional domains
Yukitomo Arao; Kenneth S. Korach
Essays Biochem (2021) 65 (6): 867–875.
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Orphan nuclear receptor 4A1 (NR4A1) and novel ligands
Stephen Safe; Rupesh Shrestha; Kumaravel Mohankumar
Essays Biochem (2021) 65 (6): 877–886.
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Ligands and DNA in the allosteric control of retinoid receptors function
Pierre Germain; Natacha Rochel; William Bourguet
Essays Biochem (2021) 65 (6): 887–899.
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Mineralocorticoid receptor actions in cardiovascular development and disease
Morag J. Young; Colin D. Clyne
Essays Biochem (2021) 65 (6): 901–911.
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Estrogen receptors and the aging brain
Silvia Maioli; Karin Leander; Per Nilsson; Ivan Nalvarte
Essays Biochem (2021) 65 (6): 913–925.
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Nuclear receptor Nur77: its role in chronic inflammatory diseases
Sanne C. Lith; Carlie J.M. de Vries
Essays Biochem (2021) 65 (6): 927–939.
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Functional roles of female sex hormones and their nuclear receptors in cervical cancer
Seoung-Ae Lee; Seunghan Baik; Sang-Hyuk Chung
Essays Biochem (2021) 65 (6): 941–950.
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Progesterone receptors in normal breast development and breast cancer
Sebastian Giulianelli; Caroline A. Lamb; Claudia Lanari
Essays Biochem (2021) 65 (6): 951–969.
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Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment
Carlos Perez Kerkvliet; Thu H. Truong; Julie Hanson Ostrander; Carol A. Lange
Essays Biochem (2021) 65 (6): 971–983.
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Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer
Corinne N. Haines; Suzanne E. Wardell; Donald P. McDonnell
Essays Biochem (2021) 65 (6): 985–1001.
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Estrogen receptor actions in colitis
Erika L. Garcia-Villatoro; Clinton D. Allred
Essays Biochem (2021) 65 (6): 1003–1013.
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Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer
Qin Tang; Ronald M. Evans
Essays Biochem (2021) 65 (6): 1015–1024.
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Roles of steroid receptors in the lung and COVID-19
Damien A. Leach; Greg N. Brooke; Charlotte L. Bevan
Essays Biochem (2021) 65 (6): 1025–1038.
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Submit your themed issue proposal here
Immune-regulating extracellular vesicles: a new frontier in autoimmune disease therapy
Advancing mRNA vaccines for infectious diseases: key components, innovations, and clinical progress
Metal coordination polymer nanoparticles for cancer therapy
Potential of bacterial outer membrane vesicles in tumor vaccine: characteristics, advancements, and future directions
Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy
  • Online ISSN 1744-1358
  • Print ISSN 0071-1365

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