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Volume 68, Issue 2
October 2024
Essays in Biochemistry Cover Image for Volume 68, Issue 2
Issue Editors
Joseph Provost;
Joseph Provost
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Kathleen Cornely;
Kathleen Cornely
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Amy Parente;
Amy Parente
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Celeste Peterson;
Celeste Peterson
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Amy Springer
Amy Springer
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All Issues
  • Cover Image

    Cover Image

    Issue cover image
    Human cytosolic malate dehydrogenase (hMDH1) rendered here using alpha fold 3, catalyzes the reversible shown. MDH is involved in a wide range of metabolic pathways, is regulated allosterically and via post-translational modifications, interacts with substrate/product-sharing enzymes and has been implicated in disease. Image by Joseph Provost.
ISSN 0071-1365
EISSN 1744-1358
In this Issue

Malate Dehydrogenase

Editorial

Uncovering malate dehydrogenase: structure, function and role in disease
Celeste N. Peterson; Kathleen Cornely; Amy D. Parente; Amy L. Springer; Joseph J. Provost
Essays Biochem (2024) 68 (2): 53–55.
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Review Articles

The structural biology and dynamics of malate dehydrogenases
Christopher E. Berndsen; Jessica K. Bell
Essays Biochem (2024) 68 (2): 57–72.
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Supplementary data
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Catalytic mechanism and kinetics of malate dehydrogenase
Laura de Lorenzo; Tyler M.M. Stack; Kristin M. Fox; Katherine M. Walstrom
Essays Biochem (2024) 68 (2): 73–82.
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Exploring the uncharted territory of the potential protein–protein interactions of cytosolic malate dehydrogenase
Joseph J. Provost; Amy D. Parente; Kristin M. Slade; Thomas J. Wiese
Essays Biochem (2024) 68 (2): 83–97.
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Is the TCA cycle malate dehydrogenase-citrate synthase metabolon an illusion?
Joy Omini; Taiwo Dele-Osibanjo; Heejeong Kim; Jing Zhang; Toshihiro Obata
Essays Biochem (2024) 68 (2): 99–106.
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Genetics of MDH in humans
Adam Haberman; Celeste N. Peterson
Essays Biochem (2024) 68 (2): 107–119.
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Physiology of malate dehydrogenase and how dysregulation leads to disease
Amy D. Parente; Danielle E. Bolland; Kathryn L. Huisinga; Joseph J. Provost
Essays Biochem (2024) 68 (2): 121–134.
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Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator
Betsy Leverett; Shane Austin; Jason Tan-Arroyo
Essays Biochem (2024) 68 (2): 135–146.
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Malate dehydrogenase as a multi-purpose target for drug discovery
Charles S. Fermaintt; Sarah A. Wacker
Essays Biochem (2024) 68 (2): 147–160.
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Roles of the oncometabolite enantiomers of 2-hydroxyglutarate and their metabolism by diverse dehydrogenases
Ivelitza Garcia; Kathleen Cornely; Celeste N. Peterson; Melanie B. Berkmen
Essays Biochem (2024) 68 (2): 161–171.
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Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules
Betsy M. Martinez-Vaz; Alicia L. Howard; Varuni K. Jamburuthugoda; Kevin P. Callahan
Essays Biochem (2024) 68 (2): 173–181.
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Phosphorylation of mammalian cytosolic and mitochondrial malate dehydrogenase: insights into regulation
Joseph J. Provost; Kathleen A Cornely; Pamela S. Mertz; Celeste N. Peterson; Sophie G. Riley; Harrison J. Tarbox; Shree R. Narasimhan; Andrew J Pulido; Amy L. Springer
Essays Biochem (2024) 68 (2): 183–198.
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Acetylation, ADP-ribosylation and methylation of malate dehydrogenase
Misty L. Kuhn; John F. Rakus; Delphine Quenet
Essays Biochem (2024) 68 (2): 199–212.
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Malate dehydrogenase: a story of diverse evolutionary radiation
Michael J. Wolyniak; Robert H. Frazier; Peter K. Gemborys; Henry E. Loehr
Essays Biochem (2024) 68 (2): 213–220.
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Malate dehydrogenase in plants: evolution, structure, and a myriad of functions
Lisa M. Baird; Christopher E. Berndsen; Jonathan D. Monroe
Essays Biochem (2024) 68 (2): 221–233.
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Malate dehydrogenase in parasitic protozoans: roles in metabolism and potential therapeutic applications
Amy L. Springer; Swati Agrawal; Eric P. Chang
Essays Biochem (2024) 68 (2): 235–251.
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Innovate and empower: the malate dehydrogenase course-based undergraduate research experiences and community of practice
Sue Ellen DeChenne-Peters; Nicole L. Scheuermann; Amy D. Parente; Jing Zhang
Essays Biochem (2024) 68 (2): 253–268.
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Purchase This Issue

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Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine
Immune activation and regulation mediated by immune cell-derived EVs (iEVs)
Immune-regulating extracellular vesicles: a new frontier in autoimmune disease therapy
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Metal coordination polymer nanoparticles for cancer therapy
  • Online ISSN 1744-1358
  • Print ISSN 0071-1365

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