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Articles

Malate dehydrogenase: a story of diverse evolutionary radiation

Open Access
Michael J. Wolyniak, Robert H. Frazier, Peter K. Gemborys, Henry E. Loehr
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 213–220.
https://doi.org/10.1042/EBC20230076
Published: 03 October 2024
View articletitled, Malate dehydrogenase: a story of diverse evolutionary radiation
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Articles

Evolution and functional diversification of yeast sugar transporters

Open Access
Lorena Donzella, Maria João Sousa, John P. Morrissey
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 811–827.
https://doi.org/10.1042/EBC20220233
Published: 13 September 2023
View articletitled, Evolution and functional diversification of yeast sugar transporters
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Includes: Supplementary data
Articles

Role of carbohydrate-active enzymes in mycorrhizal symbioses

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Yuhua Gong, Annie Lebreton, Feng Zhang, Francis Martin
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 471–478.
https://doi.org/10.1042/EBC20220127
Published: 18 April 2023
View articletitled, Role of carbohydrate-active enzymes in mycorrhizal symbioses
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Articles

Structure and function of microbial α-l-fucosidases: a mini review

Open Access
Haiyang Wu, C. David Owen, Nathalie Juge
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 399–414.
https://doi.org/10.1042/EBC20220158
Published: 18 April 2023
View articletitled, Structure and function of microbial α-l-fucosidases: a mini review
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Includes: Supplementary data
Articles

Harnessing adult-plant resistance genes to deploy durable disease resistance in crops

Open Access
Eric Dinglasan, Sambasivam Periyannan, Lee T. Hickey
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 571–580.
https://doi.org/10.1042/EBC20210096
Published: 30 September 2022
View articletitled, Harnessing adult-plant resistance genes to deploy durable disease resistance in crops
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Articles

Evolution of resistance ( R ) gene specificity

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Hanna Märkle, Isabel M.L. Saur, Remco Stam
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 551–560.
https://doi.org/10.1042/EBC20210077
Published: 30 September 2022
View articletitled, Evolution of resistance ( R ) gene specificity
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Articles

Membrane lipid raft homeostasis is directly linked to neurodegeneration

Open Access
Tobias Moll, Jack N.G. Marshall, Nikita Soni, Sai Zhang, Johnathan Cooper-Knock, Pamela J. Shaw
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 999–1011.
https://doi.org/10.1042/EBC20210026
Published: 22 December 2021
View articletitled, Membrane lipid raft homeostasis is directly linked to neurodegeneration
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Articles

Functional annotation of lncRNA in high-throughput screening

Open Access
Chi Wai Yip, Divya M. Sivaraman, Anika V. Prabhu, Jay W. Shin
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 761–773.
https://doi.org/10.1042/EBC20200061
Published: 27 October 2021
View articletitled, Functional annotation of lncRNA in high-throughput screening
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Articles

Comparative genomics in the search for conserved long noncoding RNAs

Open Access
Michał Wojciech Szcześniak, Magdalena Regina Kubiak, Elżbieta Wanowska, Izabela Makałowska
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 741–749.
https://doi.org/10.1042/EBC20200069
Published: 27 October 2021
View articletitled, Comparative genomics in the search for conserved long noncoding RNAs
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Articles

Heterogeneity among enhancer RNAs: origins, consequences and perspectives

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Khaja Mohieddin Syed, Chung-Chau Hon
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 709–721.
https://doi.org/10.1042/EBC20200064
Published: 27 October 2021
View articletitled, Heterogeneity among enhancer RNAs: origins, consequences and perspectives
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Articles

The non-coding genome in genetic brain disorders: new targets for therapy?

Open Access
Eva Medico-Salsench, Faidra Karkala, Kristina Lanko, Tahsin Stefan Barakat
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 671–683.
https://doi.org/10.1042/EBC20200121
Published: 27 October 2021
View articletitled, The non-coding genome in genetic brain disorders: new targets for therapy?
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Articles

Single-molecule optical genome mapping in nanochannels: multidisciplinarity at the nanoscale

Open Access
Jonathan Jeffet, Sapir Margalit, Yael Michaeli, Yuval Ebenstein
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 51–66.
https://doi.org/10.1042/EBC20200021
Published: 16 April 2021
View articletitled, Single-molecule optical genome mapping in nanochannels: multidisciplinarity at the nanoscale
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Articles

Construction and analysis of artificial chromosomes with de novo holocentromeres in Caenorhabditis elegans

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Zhongyang Lin, Karen Wing Yee Yuen
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 233–249.
https://doi.org/10.1042/EBC20190067
Published: 05 August 2020
View articletitled, Construction and analysis of artificial chromosomes with de novo holocentromeres in Caenorhabditis elegans
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Articles

Correction: The genetic basis of disease

Open Access
Maria Jackson, Leah Marks, Gerhard H.W. May, Joanna B. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (4): 681.
https://doi.org/10.1042/EBC20170053_COR
Published: 28 July 2020
View articletitled, Correction: The genetic basis of disease
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Articles

The role and mechanisms of DNA methylation in the oocyte

Open Access
Gintarė Sendžikaitė, Gavin Kelsey
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 691–705.
https://doi.org/10.1042/EBC20190043
Published: 29 November 2019
View articletitled, The role and mechanisms of DNA methylation in the oocyte
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Articles

DNA methylation in the vertebrate germline: balancing memory and erasure

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Oscar Ortega-Recalde, Timothy Alexander Hore
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 649–661.
https://doi.org/10.1042/EBC20190038
Published: 22 November 2019
View articletitled, DNA methylation in the vertebrate germline: balancing memory and erasure
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Articles

Latest techniques to study DNA methylation

Open Access
Quentin Gouil, Andrew Keniry
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 639–648.
https://doi.org/10.1042/EBC20190027
Published: 22 November 2019
View articletitled, Latest techniques to study DNA methylation
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Articles

Sensitivity of transcription factors to DNA methylation

Open Access
Éléa Héberlé, Anaïs Flore Bardet
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 727–741.
https://doi.org/10.1042/EBC20190033
Published: 22 November 2019
View articletitled, Sensitivity of transcription factors to DNA methylation
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Articles

Harnessing targeted DNA methylation and demethylation using dCas9

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Christian Pflueger, Tessa Swain, Ryan Lister
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 813–825.
https://doi.org/10.1042/EBC20190029
Published: 14 November 2019
View articletitled, Harnessing targeted DNA methylation and demethylation using dCas9
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Articles

Recombinant DNA technology and DNA sequencing

Open Access
Mark A. J. Roberts
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (4): 457–468.
https://doi.org/10.1042/EBC20180039
Published: 11 October 2019
View articletitled, Recombinant DNA technology and DNA sequencing
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Includes: Supplementary data
Articles

Enhancer DNA methylation: implications for gene regulation

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Allegra Angeloni, Ozren Bogdanovic
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 707–715.
https://doi.org/10.1042/EBC20190030
Published: 24 September 2019
View articletitled, Enhancer DNA methylation: implications for gene regulation
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Articles

Application of single-cell RNA sequencing methodologies in understanding haematopoiesis and immunology

Open Access
Anna M. Ranzoni, Paulina M. Strzelecka, Ana Cvejic
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (2): 217–225.
https://doi.org/10.1042/EBC20180072
Published: 11 June 2019
View articletitled, Application of single-cell RNA sequencing methodologies in understanding haematopoiesis and immunology
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Articles

Single-cell approaches to understand genome organisation throughout the cell cycle

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Sarah E. McClelland
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (2): 209–216.
https://doi.org/10.1042/EBC20180043
Published: 15 May 2019
View articletitled, Single-cell approaches to understand genome organisation throughout the cell cycle
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Articles

Chromatin fiber structural motifs as regulatory hubs of genome function?

Open Access
Manuela Moraru, Thomas Schalch
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (1): 123–132.
https://doi.org/10.1042/EBC20180065
Published: 09 April 2019
View articletitled, Chromatin fiber structural motifs as regulatory hubs of genome function?
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Articles

CTCF: a Swiss-army knife for genome organization and transcription regulation

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Luca Braccioli, Elzo de Wit
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (1): 157–165.
https://doi.org/10.1042/EBC20180069
Published: 02 April 2019
View articletitled, CTCF: a Swiss-army knife for genome organization and transcription regulation
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Articles

Nucleosome positioning and spacing: from genome-wide maps to single arrays

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Sandro Baldi
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (1): 5–14.
https://doi.org/10.1042/EBC20180058
Published: 21 February 2019
View articletitled, Nucleosome positioning and spacing: from genome-wide maps to single arrays
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Articles

The genetic basis of disease

Open Access
Maria Jackson, Leah Marks, Gerhard H.W. May, Joanna B. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (5): 643–723.
https://doi.org/10.1042/EBC20170053
Published: 03 December 2018
View articletitled, The genetic basis of disease
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Articles

Studying how genetic variants affect mechanism in biological systems

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Francesco Raimondi, Robert B. Russell
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (4): 575–582.
https://doi.org/10.1042/EBC20180021
Published: 12 October 2018
View articletitled, Studying how genetic variants affect mechanism in biological systems
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Articles

Mitochondrial DNA transcription and translation: clinical syndromes

Open Access
Veronika Boczonadi, Giulia Ricci, Rita Horvath
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 321–340.
https://doi.org/10.1042/EBC20170103
Published: 20 July 2018
View articletitled, Mitochondrial DNA transcription and translation: clinical syndromes
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Articles

Neuroimaging in mitochondrial disorders

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Mario Mascalchi, Martino Montomoli, Renzo Guerrini
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 409–421.
https://doi.org/10.1042/EBC20170109
Published: 20 July 2018
View articletitled, Neuroimaging in mitochondrial disorders
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Articles

Mitochondrial DNA replication: clinical syndromes

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Mohammed Almannai, Ayman W. El-Hattab, Fernando Scaglia
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 297–308.
https://doi.org/10.1042/EBC20170101
Published: 27 June 2018
View articletitled, Mitochondrial DNA replication: clinical syndromes
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Articles

Advancing genomic approaches to the molecular diagnosis of mitochondrial disease

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Sarah Louise Stenton, Holger Prokisch
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 399–408.
https://doi.org/10.1042/EBC20170110
Published: 27 June 2018
View articletitled, Advancing genomic approaches to the molecular diagnosis of mitochondrial disease
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Includes: Supplementary data
Articles

The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

Open Access
Anthony R. Bradley, Aude Echalier, Michael Fairhead, Claire Strain-Damerell, Paul Brennan, Alex N. Bullock, Nicola A. Burgess-Brown, Elisabeth P. Carpenter, Opher Gileadi, Brian D. Marsden, Wen Hwa Lee, Wyatt Yue, Chas Bountra, Frank von Delft
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 495–503.
https://doi.org/10.1042/EBC20170051
Published: 08 November 2017
View articletitled, The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery
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Articles

Genome instability: a conserved mechanism of ageing?

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Jan Vijg, Xiao Dong, Brandon Milholland, Lei Zhang
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (3): 305–315.
https://doi.org/10.1042/EBC20160082
Published: 26 May 2017
View articletitled, Genome instability: a conserved mechanism of ageing?
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