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Articles

Engineered bacteria and bacterial derivatives as advanced therapeutics for inflammatory bowel disease

Jingyuan Wu, Wanlin Ye, Jie Yu, Tuoyu Zhou, Nuo Zhou, Dennis K.P. Ng, Zhaoting Li
Journal: Essays in Biochemistry
Essays Biochem (2025) EBC20253003.
https://doi.org/10.1042/EBC20253003
Published: 27 February 2025
View article titled, Engineered bacteria and bacterial derivatives as advanced therapeutics for inflammatory bowel disease
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Articles

Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases

Max J. Cheetham, Yunlong Huo, Maria Stroyakovski, Li Cheng, Daniel Wan, Anne Dell, Joanne M. Santini
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 661–677.
https://doi.org/10.1042/EBC20240015
Published: 17 December 2024
View article titled, Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases
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Articles

The new age of the phage

Joanne M. Santini
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 579–581.
https://doi.org/10.1042/EBC20240037
Published: 17 December 2024
View article titled, The new age of the phage
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Articles

Phage-specific antibodies: are they a hurdle for the success of phage therapy?

Ayaka Washizaki, Arata Sakiyama, Hiroki Ando
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 633–644.
https://doi.org/10.1042/EBC20240024
Published: 17 December 2024
View article titled, Phage-specific antibodies: are they a hurdle for the success of phage therapy?
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Articles

A comparative guide to expression systems for phage lysin production

Emma Cremelie, Roberto Vázquez, Yves Briers
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 645–659.
https://doi.org/10.1042/EBC20240019
Published: 17 December 2024
View article titled, A comparative guide to expression systems for phage lysin production
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Articles

Translational research priorities for bacteriophage therapeutics

Robert T. Schooley
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 621–631.
https://doi.org/10.1042/EBC20240020
Published: 17 December 2024
View article titled, Translational research priorities for bacteriophage therapeutics
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Articles

Phage diversity in One Health

Hannah V. Pye, Revathy Krishnamurthi, Ryan Cook, Evelien M. Adriaenssens
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 607–619.
https://doi.org/10.1042/EBC20240012
Published: 17 December 2024
View article titled, Phage diversity in One Health
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Includes: Supplementary data
Articles

Characteristics of phage-plasmids and their impact on microbial communities

Ruweyda Sayid, Anne W.M. van den Hurk, Daniela Rothschild-Rodriguez, Hilde Herrema, Patrick A. de Jonge, Franklin L. Nobrega
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 583–592.
https://doi.org/10.1042/EBC20240014
Published: 17 December 2024
View article titled, Characteristics of phage-plasmids and their impact on microbial communities
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Articles

A roadmap of isolating and investigating bacteriophage infecting human gut anaerobes

Cong Liu, Bo Xing, Zhuoran Li, Junhua Li, Minfeng Xiao
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 593–605.
https://doi.org/10.1042/EBC20240116
Published: 17 December 2024
View article titled, A roadmap of isolating and investigating bacteriophage infecting human gut anaerobes
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Articles

Understanding and computational design of genetic circuits of metabolic networks

Alicia Berkvens, Luis Salinas, Maaike Remeijer, Robert Planqué, Bas Teusink, Frank J. Bruggeman
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (1): 41–51.
https://doi.org/10.1042/EBC20230045
Published: 30 April 2024
View article titled, Understanding and computational design of genetic circuits of metabolic networks
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Articles

Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance

Shane G. Downes, Sean Doyle, Gary W. Jones, Rebecca A. Owens
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 769–780.
https://doi.org/10.1042/EBC20220222
Published: 13 September 2023
View article titled, Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance
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Articles

Evolution and functional diversification of yeast sugar transporters

Lorena Donzella, Maria João Sousa, John P. Morrissey
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 811–827.
https://doi.org/10.1042/EBC20220233
Published: 13 September 2023
View article titled, Evolution and functional diversification of yeast sugar transporters
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Includes: Supplementary data
Articles

The role of the Mediator complex in fungal pathogenesis and response to antifungal agents

James O'Connor-Moneley, Leenah Alaalm, Gary P. Moran, Derek J. Sullivan
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 843–851.
https://doi.org/10.1042/EBC20220238
Published: 13 September 2023
View article titled, The role of the Mediator complex in fungal pathogenesis and response to antifungal agents
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Articles

Diverse mycotoxin threats to safe food and feed cereals

Rosie L. Latham, Jeremy T. Boyle, Anna Barbano, William G. Loveman, Neil A. Brown
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 797–809.
https://doi.org/10.1042/EBC20220221
Published: 13 September 2023
View article titled, Diverse mycotoxin threats to safe food and feed cereals
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Articles

Fungal siderophore metabolism with a focus on Aspergillus fumigatus : impact on biotic interactions and potential translational applications

Isidor Happacher, Mario Aguiar, Annie Yap, Clemens Decristoforo, Hubertus Haas
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 829–842.
https://doi.org/10.1042/EBC20220252
Published: 13 September 2023
View article titled, Fungal siderophore metabolism with a focus on Aspergillus fumigatus : impact on biotic interactions and potential translational applications
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Articles

The role of methionine synthases in fungal metabolism and virulence

Jennifer Scott, Jorge Amich
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 853–863.
https://doi.org/10.1042/EBC20230007
Published: 13 September 2023
View article titled, The role of methionine synthases in fungal metabolism and virulence
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Articles

Branched-chain amino acid biosynthesis in fungi

Joel T. Steyer, Richard B. Todd
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 865–876.
https://doi.org/10.1042/EBC20230003
Published: 13 September 2023
View article titled, Branched-chain amino acid biosynthesis in fungi
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Articles

The use of immunoaffinity purification approaches coupled with LC-MS/MS offers a powerful strategy to identify protein complexes in filamentous fungi

Ingo Bauer, Özlem Sarikaya Bayram, Özgür Bayram
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 877–892.
https://doi.org/10.1042/EBC20220253
Published: 13 September 2023
View article titled, The use of immunoaffinity purification approaches coupled with LC-MS/MS offers a powerful strategy to identify protein complexes in filamentous fungi
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Articles

Functional biology and biotechnology of thermophilic viruses

Ryan K. Doss, Marike Palmer, David A. Mead, Brian P. Hedlund
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 671–684.
https://doi.org/10.1042/EBC20220209
Published: 11 August 2023
View article titled, Functional biology and biotechnology of thermophilic viruses
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Articles

Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling

Gwion B. Williams, Hairong Ma, Anna N. Khusnutdinova, Alexander F. Yakunin, Peter N. Golyshin
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 715–729.
https://doi.org/10.1042/EBC20220255
Published: 11 August 2023
View article titled, Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling
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Articles

Nitrification in acidic and alkaline environments

Gaofeng Ni, Pok Man Leung, Anne Daebeler, Jianhua Guo, Shihu Hu, Perran Cook, Graeme W. Nicol, Holger Daims, Chris Greening
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 753–768.
https://doi.org/10.1042/EBC20220194
Published: 11 August 2023
View article titled, Nitrification in acidic and alkaline environments
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Articles

Mechanisms of bioleaching: iron and sulfur oxidation by acidophilic microorganisms

Sarah Jones, Joanne M. Santini
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 685–699.
https://doi.org/10.1042/EBC20220257
Published: 11 August 2023
View article titled, Mechanisms of bioleaching: iron and sulfur oxidation by acidophilic microorganisms
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Articles

Oxidoreductases and metal cofactors in the functioning of the earth

Bruno Hay Mele, Maria Monticelli, Serena Leone, Deborah Bastoni, Bernardo Barosa, Martina Cascone, Flavia Migliaccio, Francesco Montemagno, Annarita Ricciardelli, Luca Tonietti, Alessandra Rotundi, Angelina Cordone, Donato Giovannelli
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 653–670.
https://doi.org/10.1042/EBC20230012
Published: 11 August 2023
View article titled, Oxidoreductases and metal cofactors in the functioning of the earth
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Includes: Supplementary data
Articles

Butyrate-producing colonic clostridia: picky glycan utilization specialists

Maria Louise Leth, Michael Jakob Pichler, Maher Abou Hachem
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 415–428.
https://doi.org/10.1042/EBC20220125
Published: 18 April 2023
View article titled, Butyrate-producing colonic clostridia: picky glycan utilization specialists
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Articles

Functions and specificity of bacterial carbohydrate sulfatases targeting host glycans

Ana S. Luis, Edwin A. Yates, Alan Cartmell
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 429–442.
https://doi.org/10.1042/EBC20220120
Published: 18 April 2023
View article titled, Functions and specificity of bacterial carbohydrate sulfatases targeting host glycans
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Articles

Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond!

Jessica K. Fong, Harry Brumer
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 597–613.
https://doi.org/10.1042/EBC20220124
Published: 18 April 2023
View article titled, Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond!
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Articles

Role of carbohydrate-active enzymes in mycorrhizal symbioses

Yuhua Gong, Annie Lebreton, Feng Zhang, Francis Martin
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 471–478.
https://doi.org/10.1042/EBC20220127
Published: 18 April 2023
View article titled, Role of carbohydrate-active enzymes in mycorrhizal symbioses
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Articles

Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass

Johan Larsbrink, Leila Lo Leggio
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 493–503.
https://doi.org/10.1042/EBC20220155
Published: 18 April 2023
View article titled, Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass
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Articles

Mucin utilization by gut microbiota: recent advances on characterization of key enzymes

Grete Raba, Ana S. Luis
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 345–353.
https://doi.org/10.1042/EBC20220121
Published: 18 April 2023
View article titled, Mucin utilization by gut microbiota: recent advances on characterization of key enzymes
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Articles

Structure and function of microbial α-l-fucosidases: a mini review

Haiyang Wu, C. David Owen, Nathalie Juge
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 399–414.
https://doi.org/10.1042/EBC20220158
Published: 18 April 2023
View article titled, Structure and function of microbial α-l-fucosidases: a mini review
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Includes: Supplementary data
Articles

Glycoside hydrolases active on microbial exopolysaccharide α-glucans: structures and function

Takatsugu Miyazaki
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 505–520.
https://doi.org/10.1042/EBC20220219
Published: 18 April 2023
View article titled, Glycoside hydrolases active on microbial exopolysaccharide α-glucans: structures and function
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Articles

Carbohydrate esterases involved in deacetylation of food components by the human gut microbiota

Sabina Leanti La Rosa, Lars J. Lindstad, Bjørge Westereng
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 443–454.
https://doi.org/10.1042/EBC20220161
Published: 18 April 2023
View article titled, Carbohydrate esterases involved in deacetylation of food components by the human gut microbiota
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Articles

A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment

Mirjam Czjzek, Elizabeth Ficko-Blean, Jean-Guy Berrin
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 325–329.
https://doi.org/10.1042/EBC20230004
Published: 18 April 2023
View article titled, A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment
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Articles

Functional amyloid in a lipid-like environment: a merry dance of many steps

Daniel E. Otzen
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1035–1046.
https://doi.org/10.1042/EBC20220062
Published: 16 December 2022
View article titled, Functional amyloid in a lipid-like environment: a merry dance of many steps
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Articles

3D Bioprinting for fabrication of tissue models of COVID-19 infection

Anisha Kabir, Pallab Datta, Julia Oh, Adam Williams, Veli Ozbolat, Derya Unutmaz, Ibrahim T. Ozbolat
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (3): 503–518.
https://doi.org/10.1042/EBC20200129
Published: 06 August 2021
View article titled, 3D Bioprinting for fabrication of tissue models of COVID-19 infection
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Articles

Lactic acid bacteria: little helpers for many human tasks

Michael Sauer, Nam Soo Han
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 163–171.
https://doi.org/10.1042/EBC20200133
Published: 26 July 2021
View article titled, Lactic acid bacteria: little helpers for many human tasks
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Articles

Acinetobacter baylyi ADP1—naturally competent for synthetic biology

Suvi Santala, Ville Santala
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 309–318.
https://doi.org/10.1042/EBC20200136
Published: 26 July 2021
View article titled, Acinetobacter baylyi ADP1—naturally competent for synthetic biology
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Articles

Shewanella oneidensis MR-1 as a bacterial platform for electro-biotechnology

Sota Ikeda, Yuki Takamatsu, Miyu Tsuchiya, Keigo Suga, Yugo Tanaka, Atsushi Kouzuma, Kazuya Watanabe
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 355–364.
https://doi.org/10.1042/EBC20200178
Published: 26 July 2021
View article titled, Shewanella oneidensis MR-1 as a bacterial platform for electro-biotechnology
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Articles

Metabolic engineering of Vibrio natriegens

Felix Thoma, Bastian Blombach
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 381–392.
https://doi.org/10.1042/EBC20200135
Published: 26 July 2021
View article titled, Metabolic engineering of Vibrio natriegens
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Articles

Perspectives for the application of Ustilaginaceae as biotech cell factories

Nick Wierckx, Katharina Miebach, Nina Ihling, Kai P. Hussnaetter, Jochen Büchs, Kerstin Schipper
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 365–379.
https://doi.org/10.1042/EBC20200141
Published: 26 July 2021
View article titled, Perspectives for the application of Ustilaginaceae as biotech cell factories
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Articles

Halomonas as a chassis

Jian-Wen Ye, Guo-Qiang Chen
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 393–403.
https://doi.org/10.1042/EBC20200159
Published: 26 July 2021
View article titled, Halomonas as a chassis
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Includes: Supplementary data
Articles

Something old, something new: challenges and developments in Aspergillus niger biotechnology

Timothy C. Cairns, Lars Barthel, Vera Meyer
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 213–224.
https://doi.org/10.1042/EBC20200139
Published: 26 July 2021
View article titled, Something old, something new: challenges and developments in Aspergillus niger biotechnology
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Articles

Recombinant protein secretion by Bacillus subtilis and Lactococcus lactis : pathways, applications, and innovation potential

Jolanda Neef, Jan Maarten van Dijl, Girbe Buist
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 187–195.
https://doi.org/10.1042/EBC20200171
Published: 26 July 2021
View article titled, Recombinant protein secretion by Bacillus subtilis and Lactococcus lactis : pathways, applications, and innovation potential
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Includes: Supplementary data
Articles

The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes

Christopher M. Whitford, Pablo Cruz-Morales, Jay D. Keasling, Tilmann Weber
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 261–275.
https://doi.org/10.1042/EBC20200132
Published: 26 July 2021
View article titled, The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes
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Articles

Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris

Sonakshi De, Diethard Mattanovich, Pau Ferrer, Brigitte Gasser
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 293–307.
https://doi.org/10.1042/EBC20200138
Published: 26 July 2021
View article titled, Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris
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Articles

Production of proteins and commodity chemicals using engineered Bacillus subtilis platform strain

Quanwei Zhang, Yaokang Wu, Mengyue Gong, Hongzhi Zhang, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 173–185.
https://doi.org/10.1042/EBC20210011
Published: 26 July 2021
View article titled, Production of proteins and commodity chemicals using engineered Bacillus subtilis platform strain
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Articles

Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites

Guokun Wang, Douglas B. Kell, Irina Borodina
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 277–291.
https://doi.org/10.1042/EBC20200137
Published: 26 July 2021
View article titled, Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites
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Articles

Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being

Sabrina Wolf, Judith Becker, Yota Tsuge, Hideo Kawaguchi, Akihiko Kondo, Jan Marienhagen, Michael Bott, Volker F. Wendisch, Christoph Wittmann
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 197–212.
https://doi.org/10.1042/EBC20200134
Published: 26 July 2021
View article titled, Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being
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Articles

Saccharomyces cerevisiae strains used industrially for bioethanol production

Ana Paula Jacobus, Jeferson Gross, John H. Evans, Sandra Regina Ceccato-Antonini, Andreas Karoly Gombert
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 147–161.
https://doi.org/10.1042/EBC20200160
Published: 26 July 2021
View article titled, Saccharomyces cerevisiae strains used industrially for bioethanol production
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Articles

Towards robust Pseudomonas cell factories to harbour novel biosynthetic pathways

Nora Lisa Bitzenhofer, Luzie Kruse, Stephan Thies, Benedikt Wynands, Thorsten Lechtenberg, Jakob Rönitz, Ekaterina Kozaeva, Nicolas Thilo Wirth, Christian Eberlein, Karl-Erich Jaeger, Pablo Iván Nikel, Hermann J. Heipieper, Nick Wierckx, Anita Loeschcke
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 319–336.
https://doi.org/10.1042/EBC20200173
Published: 26 July 2021
View article titled, Towards robust Pseudomonas cell factories to harbour novel biosynthetic pathways
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