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Articles

Steroid sulfatase and sulfotransferases in the estrogen and androgen action of gynecological cancers: current status and perspectives

Tea Lanišnik Rižner, Marija Gjorgoska
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 411–422.
https://doi.org/10.1042/EBC20230096
Published: 04 December 2024
View articletitled, Steroid sulfatase and sulfotransferases in the estrogen and androgen action of gynecological cancers: current status and perspectives
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Articles

Genetic variability in proteoglycan biosynthetic genes reveals new facets of heparan sulfate diversity

Mohand Ouidir Ouidja, Denis S.F. Biard, Minh Bao Huynh, Xavier Laffray, Wilton Gomez-Henao, Sandrine Chantepie, Gael Le Douaron, Nicolas Rebergue, Auriane Maïza, Heloise Merrick, Aubert De Lichy, Alwyn Dady, Oscar González-Velasco, Karla Rubio, Guillermo Barreto, Kévin Baranger, Valerie Cormier-Daire, Javier De Las Rivas, David G. Fernig, Dulce Papy-Garcia
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 555–578.
https://doi.org/10.1042/EBC20240106
Published: 04 December 2024
View articletitled, Genetic variability in proteoglycan biosynthetic genes reveals new facets of heparan sulfate diversity
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Articles

Sulfation pathways in times of change

Jonathan Wolf Mueller, Daniela Fietz, Irundika H.K. Dias
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 379–382.
https://doi.org/10.1042/EBC20230099
Published: 04 December 2024
View articletitled, Sulfation pathways in times of change
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Articles

Oxysterol sulfates in fluids, cells and tissues: how much do we know about their clinical significance, biological relevance and biophysical implications?

Ana Reis, Irundika H.K. Dias
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 401–410.
https://doi.org/10.1042/EBC20230090
Published: 04 December 2024
View articletitled, Oxysterol sulfates in fluids, cells and tissues: how much do we know about their clinical significance, biological relevance and biophysical implications?
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Articles

New concepts in the roles of AMPK in adipocyte stem cell biology

Alice E. Pollard
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 349–361.
https://doi.org/10.1042/EBC20240008
Published: 18 November 2024
View articletitled, New concepts in the roles of AMPK in adipocyte stem cell biology
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Articles

AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure

Ettore Vanni, Christophe Beauloye, Sandrine Horman, Luc Bertrand
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 363–377.
https://doi.org/10.1042/EBC20240003
Published: 18 November 2024
View articletitled, AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure
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Articles

Physiology of malate dehydrogenase and how dysregulation leads to disease

Amy D. Parente, Danielle E. Bolland, Kathryn L. Huisinga, Joseph J. Provost
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 121–134.
https://doi.org/10.1042/EBC20230085
Published: 03 October 2024
View articletitled, Physiology of malate dehydrogenase and how dysregulation leads to disease
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Articles

Acetylation, ADP-ribosylation and methylation of malate dehydrogenase

Misty L. Kuhn, John F. Rakus, Delphine Quenet
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 199–212.
https://doi.org/10.1042/EBC20230080
Published: 03 October 2024
View articletitled, Acetylation, ADP-ribosylation and methylation of malate dehydrogenase
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Articles

Genetics of MDH in humans

Adam Haberman, Celeste N. Peterson
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 107–119.
https://doi.org/10.1042/EBC20230078
Published: 03 October 2024
View articletitled, Genetics of MDH in humans
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Articles

Phosphorylation of mammalian cytosolic and mitochondrial malate dehydrogenase: insights into regulation

Joseph J. Provost, Kathleen A Cornely, Pamela S. Mertz, Celeste N. Peterson, Sophie G. Riley, Harrison J. Tarbox, Shree R. Narasimhan, Andrew J Pulido, Amy L. Springer
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 183–198.
https://doi.org/10.1042/EBC20230079
Published: 03 October 2024
View articletitled, Phosphorylation of mammalian cytosolic and mitochondrial malate dehydrogenase: insights into regulation
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Articles

Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator

Betsy Leverett, Shane Austin, Jason Tan-Arroyo
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 135–146.
https://doi.org/10.1042/EBC20230088
Published: 03 October 2024
View articletitled, Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator
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Articles

The role of IFN-γ-signalling in response to immune checkpoint blockade therapy

Chun Wai Wong, Yang Yu Huang, Adam Hurlstone
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (6): 991–1002.
https://doi.org/10.1042/EBC20230001
Published: 28 September 2023
View articletitled, The role of IFN-γ-signalling in response to immune checkpoint blockade therapy
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Articles

DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling

Otto P.G. Wheeler, Leonie Unterholzner
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (6): 905–918.
https://doi.org/10.1042/EBC20220241
Published: 28 September 2023
View articletitled, DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling
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Articles

Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning

Gwo-Jiunn H. Hwang, Rosemary K. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 893–901.
https://doi.org/10.1042/EBC20230010
Published: 13 September 2023
View articletitled, Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning
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Articles

A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment

Mirjam Czjzek, Elizabeth Ficko-Blean, Jean-Guy Berrin
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 325–329.
https://doi.org/10.1042/EBC20230004
Published: 18 April 2023
View articletitled, A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment
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Articles

Structural mass spectrometry approaches to understand multidrug efflux systems

Benjamin Russell Lewis, Ryan Lawrence, Dietmar Hammerschmid, Eamonn Reading
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 255–267.
https://doi.org/10.1042/EBC20220190
Published: 29 March 2023
View articletitled, Structural mass spectrometry approaches to understand multidrug efflux systems
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Articles

A special issue of Essays in Biochemistry on structural mass spectrometry

Hannah M. Britt, Rebecca Beveridge, Antonio N. Calabrese
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 147–149.
https://doi.org/10.1042/EBC20230006
Published: 29 March 2023
View articletitled, A special issue of Essays in Biochemistry on structural mass spectrometry
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Articles

Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R

Paula Beltran-Lobo, Matthew J. Reid, Maria Jimenez-Sanchez, Alexei Verkhratsky, Beatriz G. Perez-Nievas, Wendy Noble
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 119–130.
https://doi.org/10.1042/EBC20220079
Published: 03 March 2023
View articletitled, Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R
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Articles

Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling

Jens V. Andersen, Arne Schousboe, Petrine Wellendorph
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 77–91.
https://doi.org/10.1042/EBC20220208
Published: 03 March 2023
View articletitled, Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling
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Articles

A special issue in Essays in Biochemistry on astrocytes—more than a neuronal support network

Juan P. Bolaños
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 1–2.
https://doi.org/10.1042/EBC20230005
Published: 03 March 2023
View articletitled, A special issue in Essays in Biochemistry on astrocytes—more than a neuronal support network
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Articles

Crossroads between copper ions and amyloid formation in Parkinson’s disease

Pernilla Wittung-Stafshede
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 977–986.
https://doi.org/10.1042/EBC20220043
Published: 16 December 2022
View articletitled, Crossroads between copper ions and amyloid formation in Parkinson’s disease
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Articles

Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates

Alexander V. Fonin, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov, Boris Y. Zaslavsky, Prakash Kulkarni, Vladimir N. Uversky
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 831–847.
https://doi.org/10.1042/EBC20220052
Published: 16 December 2022
View articletitled, Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates
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Articles

Different states and the associated fates of biomolecular condensates

Srivastav Ranganathan, Junlang Liu, Eugene Shakhnovich
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 849–862.
https://doi.org/10.1042/EBC20220054
Published: 16 December 2022
View articletitled, Different states and the associated fates of biomolecular condensates
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Articles

How phosphorylation impacts intrinsically disordered proteins and their function

Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann-Petersen, Karen Skriver, Birthe B. Kragelund
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 901–913.
https://doi.org/10.1042/EBC20220060
Published: 16 December 2022
View articletitled, How phosphorylation impacts intrinsically disordered proteins and their function
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Articles

The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer

Mayra A. Marques, Guilherme A.P. de Oliveira, Jerson L. Silva
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1023–1033.
https://doi.org/10.1042/EBC20220064
Published: 16 December 2022
View articletitled, The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer
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Articles

Phase separation and other forms of α-Synuclein self-assemblies

Manisha Poudyal, Arunima Sakunthala, Semanti Mukherjee, Laxmikant Gadhe, Samir K Maji
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 987–1000.
https://doi.org/10.1042/EBC20220055
Published: 16 December 2022
View articletitled, Phase separation and other forms of α-Synuclein self-assemblies
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Articles

Shapeshifting tau: from intrinsically disordered to paired-helical filaments

Kurtis Mengham, Youssra Al-Hilaly, Sebastian Oakley, Kamillia Kasbi, Mahmoud B. Maina, Louise C. Serpell
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1001–1011.
https://doi.org/10.1042/EBC20220150
Published: 16 December 2022
View articletitled, Shapeshifting tau: from intrinsically disordered to paired-helical filaments
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Articles

Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation

Si Wu, Jitao Wen, Sarah Perrett
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 891–900.
https://doi.org/10.1042/EBC20220148
Published: 16 December 2022
View articletitled, Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation
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Articles

Unconventional R proteins in the botanical tribe Triticeae

Naveenkumar Athiyannan, Lamia Aouini, Yajun Wang, Simon G. Krattinger
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 561–569.
https://doi.org/10.1042/EBC20210081
Published: 30 September 2022
View articletitled, Unconventional R proteins in the botanical tribe Triticeae
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Articles

Case study: Co-creating a flipped feed-in approach to a virtual biochemistry lab assessment: increasing student achievement and engagement in a large, diverse cohort

Shabana Cassambai, Hannah Bridge, Palak K. Gill, Similoluwa Shobaloju, Tiziana Sgamma, Jo V. Rushworth
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 29–37.
https://doi.org/10.1042/EBC20210051
Published: 29 April 2022
View articletitled, Case study: Co-creating a flipped feed-in approach to a virtual biochemistry lab assessment: increasing student achievement and engagement in a large, diverse cohort
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Articles

Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts

Torben Lund, Rosemary K. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 45–51.
https://doi.org/10.1042/EBC20210053
Published: 29 April 2022
View articletitled, Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts
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Articles

Case study: Biochemistry without borders: a case study utilising infographics

Michelle A. Sahai, Anna Ivanova
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 65–73.
https://doi.org/10.1042/EBC20210040
Published: 29 April 2022
View articletitled, Case study: Biochemistry without borders: a case study utilising infographics
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Articles

Perspective on pros and cons of microlearning in health education

Eser Yıldırım Sozmen
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 39–44.
https://doi.org/10.1042/EBC20210047
Published: 29 April 2022
View articletitled, Perspective on pros and cons of microlearning in health education
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Articles

Rab GTPases in Parkinson's disease: a primer

Antonio Jesús Lara Ordóñez, Rachel Fasiczka, Yahaira Naaldijk, Sabine Hilfiker
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 961–974.
https://doi.org/10.1042/EBC20210016
Published: 22 December 2021
View articletitled, Rab GTPases in Parkinson's disease: a primer
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Articles

ATP-binding cassette transporters and neurodegenerative diseases

Jared S. Katzeff, Woojin Scott Kim
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 1013–1024.
https://doi.org/10.1042/EBC20210012
Published: 22 December 2021
View articletitled, ATP-binding cassette transporters and neurodegenerative diseases
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Articles

Glucocerebrosidase dysfunction in neurodegenerative disease

Sarah M. Brooker, Dimitri Krainc
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 873–883.
https://doi.org/10.1042/EBC20210018
Published: 22 December 2021
View articletitled, Glucocerebrosidase dysfunction in neurodegenerative disease
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Articles

Retromer dependent changes in cellular homeostasis and Parkinson's disease

Zhe Yang, Zebin Li, Rohan D. Teasdale
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 987–998.
https://doi.org/10.1042/EBC20210023
Published: 22 December 2021
View articletitled, Retromer dependent changes in cellular homeostasis and Parkinson's disease
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Articles

Cryo-EM structures of τ filaments from human brain

Michel Goedert
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 949–959.
https://doi.org/10.1042/EBC20210025
Published: 22 December 2021
View articletitled, Cryo-EM structures of τ filaments from human brain
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Articles

LRRK2 signaling in neurodegeneration: two decades of progress

Lucia Iannotta, Elisa Greggio
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 859–872.
https://doi.org/10.1042/EBC20210013
Published: 22 December 2021
View articletitled, LRRK2 signaling in neurodegeneration: two decades of progress
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Articles

Vesicular dysfunction and pathways to neurodegeneration

Patrick A. Lewis
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 941–948.
https://doi.org/10.1042/EBC20210034
Published: 22 December 2021
View articletitled, Vesicular dysfunction and pathways to neurodegeneration
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Articles

PINK1 signalling in neurodegenerative disease

Daniel R. Whiten, Dezerae Cox, Carolyn M. Sue
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 913–923.
https://doi.org/10.1042/EBC20210036
Published: 22 December 2021
View articletitled, PINK1 signalling in neurodegenerative disease
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Articles

Roles of steroid receptors in the lung and COVID-19

Damien A. Leach, Greg N. Brooke, Charlotte L. Bevan
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 1025–1038.
https://doi.org/10.1042/EBC20210005
Published: 26 November 2021
View articletitled, Roles of steroid receptors in the lung and COVID-19
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Articles

Estrogen receptor actions in colitis

Erika L. Garcia-Villatoro, Clinton D. Allred
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 1003–1013.
https://doi.org/10.1042/EBC20210010
Published: 26 November 2021
View articletitled, Estrogen receptor actions in colitis
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Articles

Mineralocorticoid receptor actions in cardiovascular development and disease

Morag J. Young, Colin D. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 901–911.
https://doi.org/10.1042/EBC20210006
Published: 26 November 2021
View articletitled, Mineralocorticoid receptor actions in cardiovascular development and disease
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Articles

The non-coding genome in genetic brain disorders: new targets for therapy?

Eva Medico-Salsench, Faidra Karkala, Kristina Lanko, Tahsin Stefan Barakat
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 671–683.
https://doi.org/10.1042/EBC20200121
Published: 27 October 2021
View articletitled, The non-coding genome in genetic brain disorders: new targets for therapy?
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Articles

3D printing technologies for in vitro vaccine testing platforms and vaccine delivery systems against infectious diseases

Ji Young Choi, Bhushan Mahadik, John P. Fisher
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (3): 519–531.
https://doi.org/10.1042/EBC20200105
Published: 06 August 2021
View articletitled, 3D printing technologies for in vitro vaccine testing platforms and vaccine delivery systems against infectious diseases
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Articles

Guardians of the genome: DNA damage and repair

Qian Wu
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 683–685.
https://doi.org/10.1042/EBC20200109
Published: 23 October 2020
View articletitled, Guardians of the genome: DNA damage and repair
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Articles

RecQ helicases in DNA repair and cancer targets

Joseph A. Newman, Opher Gileadi
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 819–830.
https://doi.org/10.1042/EBC20200012
Published: 23 October 2020
View articletitled, RecQ helicases in DNA repair and cancer targets
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Articles

Alerting the immune system to DNA damage: micronuclei as mediators

Kate M. MacDonald, Soraya Benguerfi, Shane M. Harding
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 753–764.
https://doi.org/10.1042/EBC20200016
Published: 26 August 2020
View articletitled, Alerting the immune system to DNA damage: micronuclei as mediators
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Articles

Lyso-glycosphingolipids: presence and consequences

Marco van Eijk, Maria J. Ferraz, Rolf G. Boot, Johannes M.F.G. Aerts
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 565–578.
https://doi.org/10.1042/EBC20190090
Published: 18 August 2020
View articletitled, Lyso-glycosphingolipids: presence and consequences
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