1-35 of 35
Pharmacology & Toxicology
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Phage diversity in One Health

Open Access
Hannah V. Pye, Revathy Krishnamurthi, Ryan Cook, Evelien M. Adriaenssens
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (5): 607–619.
https://doi.org/10.1042/EBC20240012
Published: 17 December 2024
View articletitled, Phage diversity in One Health
Open the PDF for Phage diversity in One Health in another window
Includes: Supplementary data
Articles

Sulfation pathways in the maintenance of functional beta-cell mass and implications for diabetes

Open Access
Jonathan Wolf Mueller, Patricia Thomas, Louise Torp Dalgaard, Gabriela da Silva Xavier
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 509–522.
https://doi.org/10.1042/EBC20240034
Published: 04 December 2024
View articletitled, Sulfation pathways in the maintenance of functional beta-cell mass and implications for diabetes
Open the PDF for Sulfation pathways in the maintenance of functional beta-cell mass and implications for diabetes in another window
Articles

The role of IFN-γ-signalling in response to immune checkpoint blockade therapy

Open Access
Chun Wai Wong, Yang Yu Huang, Adam Hurlstone
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (6): 991–1002.
https://doi.org/10.1042/EBC20230001
Published: 28 September 2023
View articletitled, The role of IFN-γ-signalling in response to immune checkpoint blockade therapy
Open the PDF for The role of IFN-γ-signalling in response to immune checkpoint blockade therapy in another window
Articles

Charge detection mass spectrometry for the analysis of viruses and virus-like particles

Available to Purchase
Lohra M. Miller, Martin F. Jarrold
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 315–323.
https://doi.org/10.1042/EBC20220101
Published: 29 March 2023
View articletitled, Charge detection mass spectrometry for the analysis of viruses and virus-like particles
Open the PDF for Charge detection mass spectrometry for the analysis of viruses and virus-like particles in another window
Articles

WNT signaling and cancer stemness

Open Access
Masuko Katoh, Masaru Katoh
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 319–331.
https://doi.org/10.1042/EBC20220016
Published: 16 September 2022
View articletitled, WNT signaling and cancer stemness
Open the PDF for WNT signaling and cancer stemness in another window
Articles

Biomechanics of cancer stem cells

Open Access
Xi Chen, Kai Tang, Xueyi Li, Cunyu Zhang, Ying Xin, Keming Li, Youhua Tan
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 359–369.
https://doi.org/10.1042/EBC20220014
Published: 16 September 2022
View articletitled, Biomechanics of cancer stem cells
Open the PDF for Biomechanics of cancer stem cells in another window
Articles

Membrane lipid raft homeostasis is directly linked to neurodegeneration

Open Access
Tobias Moll, Jack N.G. Marshall, Nikita Soni, Sai Zhang, Johnathan Cooper-Knock, Pamela J. Shaw
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 999–1011.
https://doi.org/10.1042/EBC20210026
Published: 22 December 2021
View articletitled, Membrane lipid raft homeostasis is directly linked to neurodegeneration
Open the PDF for Membrane lipid raft homeostasis is directly linked to neurodegeneration in another window
Articles

Progesterone receptors in normal breast development and breast cancer

Available to Purchase
Sebastian Giulianelli, Caroline A. Lamb, Claudia Lanari
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 951–969.
https://doi.org/10.1042/EBC20200163
Published: 26 November 2021
View articletitled, Progesterone receptors in normal breast development and breast cancer
Open the PDF for Progesterone receptors in normal breast development and breast cancer in another window
Articles

Roles of steroid receptors in the lung and COVID-19

Open Access
Damien A. Leach, Greg N. Brooke, Charlotte L. Bevan
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 1025–1038.
https://doi.org/10.1042/EBC20210005
Published: 26 November 2021
View articletitled, Roles of steroid receptors in the lung and COVID-19
Open the PDF for Roles of steroid receptors in the lung and COVID-19 in another window
Articles

Nuclear receptors: from molecular mechanisms to therapeutics

Open Access
Daniel E. Frigo, Maria Bondesson, Cecilia Williams
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 847–856.
https://doi.org/10.1042/EBC20210020
Published: 26 November 2021
View articletitled, Nuclear receptors: from molecular mechanisms to therapeutics
Open the PDF for Nuclear receptors: from molecular mechanisms to therapeutics in another window
Articles

SINEUPs: a novel toolbox for RNA therapeutics

Open Access
Stefano Espinoza, Carlotta Bon, Paola Valentini, Bianca Pierattini, Abraham Tettey Matey, Devid Damiani, Salvatore Pulcrano, Remo Sanges, Francesca Persichetti, Hazuki Takahashi, Piero Carninci, Claudio Santoro, Diego Cotella, Stefano Gustincich
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 775–789.
https://doi.org/10.1042/EBC20200114
Published: 27 October 2021
View articletitled, SINEUPs: a novel toolbox for RNA therapeutics
Open the PDF for SINEUPs: a novel toolbox for RNA therapeutics in another window
Articles

Targeting RNA structures in diseases with small molecules

Open Access
Yanqiu Shao, Qiangfeng Cliff Zhang
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (6): 955–966.
https://doi.org/10.1042/EBC20200011
Published: 07 December 2020
View articletitled, Targeting RNA structures in diseases with small molecules
Open the PDF for Targeting RNA structures in diseases with small molecules in another window
Articles

Specialized pro-resolving mediator network: an update on production and actions

Available to Purchase
Nan Chiang, Charles N. Serhan
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 443–462.
https://doi.org/10.1042/EBC20200018
Published: 04 September 2020
View articletitled, Specialized pro-resolving mediator network: an update on production and actions
Open the PDF for Specialized pro-resolving mediator network: an update on production and actions in another window
Articles

Correction: Base excision repair and its implications to cancer therapy

Open Access
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 845.
https://doi.org/10.1042/EBC20200013_COR
Published: 29 July 2020
View articletitled, Correction: Base excision repair and its implications to cancer therapy
Open the PDF for Correction: Base excision repair and its implications to cancer therapy in another window
Articles

Base excision repair and its implications to cancer therapy

Open Access
Gabrielle J. Grundy, Jason L. Parsons
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 831–843.
https://doi.org/10.1042/EBC20200013
Published: 10 July 2020
View articletitled, Base excision repair and its implications to cancer therapy
Open the PDF for Base excision repair and its implications to cancer therapy in another window
Articles

Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining

Open Access
Antonia Kefala Stavridi, Robert Appleby, Shikang Liang, Tom L. Blundell, Amanda K. Chaplin
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 791–806.
https://doi.org/10.1042/EBC20190092
Published: 24 June 2020
View articletitled, Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
Open the PDF for Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining in another window
Articles

Basement membrane collagens and disease mechanisms

Open Access
Anna Gatseva, Yuan Yan Sin, Gaia Brezzo, Tom Van Agtmael
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (3): 297–312.
https://doi.org/10.1042/EBC20180071
Published: 06 August 2019
View articletitled, Basement membrane collagens and disease mechanisms
Open the PDF for Basement membrane collagens and disease mechanisms in another window
Articles

Exploiting vulnerabilities in cancer signalling networks to combat targeted therapy resistance

Open Access
Peter T. Harrison, Paul H. Huang
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (4): 583–593.
https://doi.org/10.1042/EBC20180016
Published: 02 August 2018
View articletitled, Exploiting vulnerabilities in cancer signalling networks to combat targeted therapy resistance
Open the PDF for Exploiting vulnerabilities in cancer signalling networks to combat targeted therapy resistance in another window
Articles

Clinical syndromes associated with mtDNA mutations: where we stand after 30 years

Available to Purchase
Valerio Carelli, Chiara La Morgia
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 235–254.
https://doi.org/10.1042/EBC20170097
Published: 20 July 2018
View articletitled, Clinical syndromes associated with mtDNA mutations: where we stand after 30 years
Open the PDF for Clinical syndromes associated with mtDNA mutations: where we stand after 30 years in another window
Articles

Coenzyme Q 10 deficiencies: pathways in yeast and humans

Open Access
Agape M. Awad, Michelle C. Bradley, Lucía Fernández-del-Río, Anish Nag, Hui S. Tsui, Catherine F. Clarke
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 361–376.
https://doi.org/10.1042/EBC20170106
Published: 06 July 2018
View articletitled, Coenzyme Q 10 deficiencies: pathways in yeast and humans
Open the PDF for Coenzyme Q 10 deficiencies: pathways in yeast and humans in another window
Articles

Natural history of mitochondrial disorders: a systematic review

Available to Purchase
Nandaki Keshavan, Shamima Rahman
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 423–442.
https://doi.org/10.1042/EBC20170108
Published: 06 July 2018
View articletitled, Natural history of mitochondrial disorders: a systematic review
Open the PDF for Natural history of mitochondrial disorders: a systematic review in another window
Articles

Advances in methods for reducing mitochondrial DNA disease by replacing or manipulating the mitochondrial genome

Open Access
Pavandeep K. Rai, Lyndsey Craven, Kurt Hoogewijs, Oliver M. Russell, Robert N. Lightowlers
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (3): 455–465.
https://doi.org/10.1042/EBC20170113
Published: 27 June 2018
View articletitled, Advances in methods for reducing mitochondrial DNA disease by replacing or manipulating the mitochondrial genome
Open the PDF for Advances in methods for reducing mitochondrial DNA disease by replacing or manipulating the mitochondrial genome in another window
Articles

Exosomes and cardiovascular cell–cell communication

Available to Purchase
Adam J. Poe, Anne A. Knowlton
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (2): 193–204.
https://doi.org/10.1042/EBC20170081
Published: 01 May 2018
View articletitled, Exosomes and cardiovascular cell–cell communication
Open the PDF for Exosomes and cardiovascular cell–cell communication in another window
Articles

Dysregulation of autophagy as a common mechanism in lysosomal storage diseases

Open Access
Elena Seranova, Kyle J. Connolly, Malgorzata Zatyka, Tatiana R. Rosenstock, Timothy Barrett, Richard I. Tuxworth, Sovan Sarkar
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (6): 733–749.
https://doi.org/10.1042/EBC20170055
Published: 12 December 2017
View articletitled, Dysregulation of autophagy as a common mechanism in lysosomal storage diseases
Open the PDF for Dysregulation of autophagy as a common mechanism in lysosomal storage diseases in another window
Articles

Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking

Open Access
Jane Fraser, Ainara G. Cabodevilla, Joanne Simpson, Noor Gammoh
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (6): 597–607.
https://doi.org/10.1042/EBC20170091
Published: 12 December 2017
View articletitled, Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking
Open the PDF for Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking in another window
Articles

NMR in structure-based drug design

Available to Purchase
Marta G. Carneiro, Eiso AB, Stephan Theisgen, Gregg Siegal
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 485–493.
https://doi.org/10.1042/EBC20170037
Published: 08 November 2017
View articletitled, NMR in structure-based drug design
Open the PDF for NMR in structure-based drug design in another window
Articles

Structure-based drug design: aiming for a perfect fit

Open Access
Rob L.M. van Montfort, Paul Workman
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 431–437.
https://doi.org/10.1042/EBC20170052
Published: 08 November 2017
View articletitled, Structure-based drug design: aiming for a perfect fit
Open the PDF for Structure-based drug design: aiming for a perfect fit in another window
Articles

Fragment-based drug discovery and its application to challenging drug targets

Available to Purchase
Amanda J. Price, Steven Howard, Benjamin D. Cons
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 475–484.
https://doi.org/10.1042/EBC20170029
Published: 08 November 2017
View articletitled, Fragment-based drug discovery and its application to challenging drug targets
Open the PDF for Fragment-based drug discovery and its application to challenging drug targets in another window
Articles

Current perspectives in fragment-based lead discovery (FBLD)

Open Access
Bas Lamoree, Roderick E. Hubbard
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 453–464.
https://doi.org/10.1042/EBC20170028
Published: 08 November 2017
View articletitled, Current perspectives in fragment-based lead discovery (FBLD)
Open the PDF for Current perspectives in fragment-based lead discovery (FBLD) in another window
Articles

Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders

Open Access
Scott J. Hughes, Alessio Ciulli
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 505–516.
https://doi.org/10.1042/EBC20170041
Published: 08 November 2017
View articletitled, Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders
Open the PDF for Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders in another window
Articles

Protein degradation: a validated therapeutic strategy with exciting prospects

Available to Purchase
Honorine Lebraud, Tom D. Heightman
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (5): 517–527.
https://doi.org/10.1042/EBC20170030
Published: 02 October 2017
View articletitled, Protein degradation: a validated therapeutic strategy with exciting prospects
Open the PDF for Protein degradation: a validated therapeutic strategy with exciting prospects in another window
Articles

Insights into drug resistance mechanisms in Clostridium difficile

Available to Purchase
Phurt Harnvoravongchai, Methinee Pipatthana, Surang Chankhamhaengdecha, Tavan Janvilisri
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (1): 81–88.
https://doi.org/10.1042/EBC20160062
Published: 03 March 2017
View articletitled, Insights into drug resistance mechanisms in Clostridium difficile
Open the PDF for Insights into drug resistance mechanisms in Clostridium difficile in another window
Articles

Microfluidics: innovative approaches for rapid diagnosis of antibiotic-resistant bacteria

Available to Purchase
Amornrat Aroonnual, Tavan Janvilisri, Puey Ounjai, Surang Chankhamhaengdecha
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (1): 91–101.
https://doi.org/10.1042/EBC20160059
Published: 03 March 2017
View articletitled, Microfluidics: innovative approaches for rapid diagnosis of antibiotic-resistant bacteria
Open the PDF for Microfluidics: innovative approaches for rapid diagnosis of antibiotic-resistant bacteria in another window
Articles

Resistance to antifungal therapies

Available to Purchase
Rajendra Prasad, Atanu Banerjee, Abdul Haseeb Shah
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (1): 157–166.
https://doi.org/10.1042/EBC20160067
Published: 03 March 2017
View articletitled, Resistance to antifungal therapies
Open the PDF for Resistance to antifungal therapies in another window
Articles

Polishing the tarnished silver bullet: the quest for new antibiotics

Open Access
Mark A.T. Blaskovich, Mark S. Butler, Matthew A. Cooper
Journal: Essays in Biochemistry
Essays Biochem (2017) 61 (1): 103–114.
https://doi.org/10.1042/EBC20160077
Published: 03 March 2017
View articletitled, Polishing the tarnished silver bullet: the quest for new antibiotics
Open the PDF for Polishing the tarnished silver bullet: the quest for new antibiotics in another window