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Articles

Quantification of persulfidation on specific proteins: are we nearly there yet?

Hongling Liu, Florentina Negoita, Matthew Brook, Kei Sakamoto, Nicholas M. Morton
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 467–478.
https://doi.org/10.1042/EBC20230095
Published: 04 December 2024
View article titled, Quantification of persulfidation on specific proteins: are we nearly there yet?
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Articles

New developments in AMPK and mTORC1 cross-talk

William J. Smiles, Ashley J. Ovens, Bruce E. Kemp, Sandra Galic, Janni Petersen, Jonathan S. Oakhill
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 321–336.
https://doi.org/10.1042/EBC20240007
Published: 18 November 2024
View article titled, New developments in AMPK and mTORC1 cross-talk
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Articles

How mass spectrometry can be exploited to study AMPK

Mark H. Rider, Didier Vertommen, Manuel Johanns
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 283–294.
https://doi.org/10.1042/EBC20240009
Published: 18 November 2024
View article titled, How mass spectrometry can be exploited to study AMPK
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Articles

AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure

Ettore Vanni, Christophe Beauloye, Sandrine Horman, Luc Bertrand
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 363–377.
https://doi.org/10.1042/EBC20240003
Published: 18 November 2024
View article titled, AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure
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Articles

NUAK: never underestimate a kinase

George L. Skalka, Declan Whyte, Dominika Lubawska, Daniel J. Murphy
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 295–307.
https://doi.org/10.1042/EBC20240005
Published: 18 November 2024
View article titled, NUAK: never underestimate a kinase
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Articles

Does AMPK bind glycogen in skeletal muscle or is the relationship correlative?

Barnaby P. Frankish, Robyn M. Murphy
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 337–347.
https://doi.org/10.1042/EBC20240006
Published: 18 November 2024
View article titled, Does AMPK bind glycogen in skeletal muscle or is the relationship correlative?
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Articles

CaMKK2: bridging the gap between Ca 2+ signaling and energy-sensing

Luke M. McAloon, Abbey G. Muller, Kevin Nay, Eudora L. Lu, Benoit Smeuninx, Anthony R. Means, Mark A. Febbraio, John W. Scott
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 309–320.
https://doi.org/10.1042/EBC20240011
Published: 18 November 2024
View article titled, CaMKK2: bridging the gap between Ca 2+ signaling and energy-sensing
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Articles

Understanding metabolic plasticity at single cell resolution

Christina C. Abbate, Jason Hu, John G. Albeck
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 273–281.
https://doi.org/10.1042/EBC20240002
Published: 18 November 2024
View article titled, Understanding metabolic plasticity at single cell resolution
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Articles

A special issue of Essays in Biochemistry on AMPK and AMPK-related kinases

Ian P. Salt, David Carling
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (3): 269–271.
https://doi.org/10.1042/EBC20240038
Published: 18 November 2024
View article titled, A special issue of Essays in Biochemistry on AMPK and AMPK-related kinases
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Articles

T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures

Thomas A.E. Elliot, David A.J. Lecky, David Bending
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (6): 967–977.
https://doi.org/10.1042/EBC20220247
Published: 28 September 2023
View article titled, T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures
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Articles

DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling

Otto P.G. Wheeler, Leonie Unterholzner
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (6): 905–918.
https://doi.org/10.1042/EBC20220241
Published: 28 September 2023
View article titled, DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling
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Articles

Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?

Ignacio Fernández-Moncada, Giovanni Marsicano
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 49–61.
https://doi.org/10.1042/EBC20220089
Published: 03 March 2023
View article titled, Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?
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Articles

Long-term plasticity of astrocytic phenotypes and their control by neurons in health and disease

Kyle S. Wardlaw, Giles E. Hardingham
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 39–47.
https://doi.org/10.1042/EBC20220090
Published: 03 March 2023
View article titled, Long-term plasticity of astrocytic phenotypes and their control by neurons in health and disease
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Articles

Astrocyte heterogeneity and interactions with local neural circuits

Matthew G. Holt
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 93–106.
https://doi.org/10.1042/EBC20220136
Published: 03 March 2023
View article titled, Astrocyte heterogeneity and interactions with local neural circuits
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Articles

Astrocytes in memory formation and maintenance

Kirsten Bohmbach, Christian Henneberger, Johannes Hirrlinger
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 107–117.
https://doi.org/10.1042/EBC20220091
Published: 03 March 2023
View article titled, Astrocytes in memory formation and maintenance
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Articles

Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R

Paula Beltran-Lobo, Matthew J. Reid, Maria Jimenez-Sanchez, Alexei Verkhratsky, Beatriz G. Perez-Nievas, Wendy Noble
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 119–130.
https://doi.org/10.1042/EBC20220079
Published: 03 March 2023
View article titled, Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R
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Articles

Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates

Alexander V. Fonin, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov, Boris Y. Zaslavsky, Prakash Kulkarni, Vladimir N. Uversky
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 831–847.
https://doi.org/10.1042/EBC20220052
Published: 16 December 2022
View article titled, Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates
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Articles

How phosphorylation impacts intrinsically disordered proteins and their function

Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann-Petersen, Karen Skriver, Birthe B. Kragelund
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 901–913.
https://doi.org/10.1042/EBC20220060
Published: 16 December 2022
View article titled, How phosphorylation impacts intrinsically disordered proteins and their function
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Articles

Evolution of SLiM-mediated hijack functions in intrinsically disordered viral proteins

Juliana Glavina, Nicolas Palopoli, Lucía Beatriz Chemes
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 945–958.
https://doi.org/10.1042/EBC20220059
Published: 16 December 2022
View article titled, Evolution of SLiM-mediated hijack functions in intrinsically disordered viral proteins
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Articles

New molecules in plant defence against pathogens

Laura Eccleston, Alessandro Brambilla, A. Corina Vlot
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 683–693.
https://doi.org/10.1042/EBC20210076
Published: 30 September 2022
View article titled, New molecules in plant defence against pathogens
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Articles

Salicylic acid and jasmonic acid crosstalk in plant immunity

Shiji Hou, Kenichi Tsuda
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 647–656.
https://doi.org/10.1042/EBC20210090
Published: 30 September 2022
View article titled, Salicylic acid and jasmonic acid crosstalk in plant immunity
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Articles

Apoplastic and vascular defences

Martin Darino, Kostya Kanyuka, Kim E. Hammond-Kosack
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 595–605.
https://doi.org/10.1042/EBC20220159
Published: 30 September 2022
View article titled, Apoplastic and vascular defences
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Articles

What’s new in protein kinase/phosphatase signalling in the control of plant immunity?

Jessica Erickson, Philipp Weckwerth, Tina Romeis, Justin Lee
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 621–634.
https://doi.org/10.1042/EBC20210088
Published: 30 September 2022
View article titled, What’s new in protein kinase/phosphatase signalling in the control of plant immunity?
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Articles

Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling

Jian Chen, Xiaoxiao Zhang, John P. Rathjen, Peter N. Dodds
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 471–483.
https://doi.org/10.1042/EBC20210072
Published: 30 September 2022
View article titled, Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling
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Articles

Immune priming in plants: from the onset to transgenerational maintenance

Agatha Cooper, Jurriaan Ton
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 635–646.
https://doi.org/10.1042/EBC20210082
Published: 30 September 2022
View article titled, Immune priming in plants: from the onset to transgenerational maintenance
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Articles

Interplay between phytohormone signalling pathways in plant defence – other than salicylic acid and jasmonic acid

Eleanor Gilroy, Susan Breen
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 657–671.
https://doi.org/10.1042/EBC20210089
Published: 30 September 2022
View article titled, Interplay between phytohormone signalling pathways in plant defence – other than salicylic acid and jasmonic acid
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Articles

Targeting protein kinases in cancer stem cells

Chin Ngok Chu, Terence Kin Wah Lee
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 399–412.
https://doi.org/10.1042/EBC20220002
Published: 16 September 2022
View article titled, Targeting protein kinases in cancer stem cells
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Articles

A special issue of Essays in Biochemistry on cancer stem cells

Fan Ying, Terence Kin Wah Lee
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 287–289.
https://doi.org/10.1042/EBC20220049
Published: 16 September 2022
View article titled, A special issue of Essays in Biochemistry on cancer stem cells
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Articles

WNT signaling and cancer stemness

Masuko Katoh, Masaru Katoh
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 319–331.
https://doi.org/10.1042/EBC20220016
Published: 16 September 2022
View article titled, WNT signaling and cancer stemness
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Articles

Uncovering protein function: from classification to complexes

Rhiannon Morris, Katrina A. Black, Elliott J. Stollar
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (3): 255–285.
https://doi.org/10.1042/EBC20200108
Published: 10 August 2022
View article titled, Uncovering protein function: from classification to complexes
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Articles

Activation and turnover of the plant immune signaling kinase BIK1: a fine balance

Márcia Gonçalves Dias, Faranak Soleimani, Jacqueline Monaghan
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 207–218.
https://doi.org/10.1042/EBC20210071
Published: 05 August 2022
View article titled, Activation and turnover of the plant immune signaling kinase BIK1: a fine balance
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Articles

RNA-binding proteins and their role in translational regulation in plants

José Antonio Duarte-Conde, Gemma Sans-Coll, Catharina Merchante
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 87–97.
https://doi.org/10.1042/EBC20210069
Published: 05 August 2022
View article titled, RNA-binding proteins and their role in translational regulation in plants
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Articles

HECT ubiquitin ligases as accessory proteins of the plant proteasome

Zhishuo Wang, Steven H. Spoel
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 135–145.
https://doi.org/10.1042/EBC20210064
Published: 05 August 2022
View article titled, HECT ubiquitin ligases as accessory proteins of the plant proteasome
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Articles

The emerging roles of deubiquitinases in plant proteostasis

Michael J. Skelly
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 147–154.
https://doi.org/10.1042/EBC20210060
Published: 05 August 2022
View article titled, The emerging roles of deubiquitinases in plant proteostasis
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Articles

Ubiquitin ligases at the nexus of plant responses to biotic and abiotic stresses

Sophia L. Stone
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 123–133.
https://doi.org/10.1042/EBC20210070
Published: 05 August 2022
View article titled, Ubiquitin ligases at the nexus of plant responses to biotic and abiotic stresses
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Articles

Plant proteostasis: a proven and promising target for crop improvement

Frederica L. Theodoulou, Beatriz Orosa-Puente, Marco Trujillo, Vicente Rubio
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 75–85.
https://doi.org/10.1042/EBC20210078
Published: 05 August 2022
View article titled, Plant proteostasis: a proven and promising target for crop improvement
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Articles

E2 ubiquitin-conjugating enzymes (UBCs): drivers of ubiquitin signalling in plants

Carla Brillada, Marco Trujillo
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (2): 99–110.
https://doi.org/10.1042/EBC20210093
Published: 05 August 2022
View article titled, E2 ubiquitin-conjugating enzymes (UBCs): drivers of ubiquitin signalling in plants
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Includes: Supplementary data
Articles

Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM

Ping Yi, Xinzhe Yu, Zhao Wang, Bert W. O'Malley
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 857–866.
https://doi.org/10.1042/EBC20210019
Published: 26 November 2021
View article titled, Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM
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Articles

Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment

Carlos Perez Kerkvliet, Thu H. Truong, Julie Hanson Ostrander, Carol A. Lange
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 971–983.
https://doi.org/10.1042/EBC20200165
Published: 26 November 2021
View article titled, Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment
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Articles

Nuclear receptors: from molecular mechanisms to therapeutics

Daniel E. Frigo, Maria Bondesson, Cecilia Williams
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 847–856.
https://doi.org/10.1042/EBC20210020
Published: 26 November 2021
View article titled, Nuclear receptors: from molecular mechanisms to therapeutics
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Articles

Mammalian lipids: structure, synthesis and function

Shamshad Cockcroft
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (5): 813–845.
https://doi.org/10.1042/EBC20200067
Published: 02 November 2021
View article titled, Mammalian lipids: structure, synthesis and function
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Articles

Guardians of the genome: DNA damage and repair

Qian Wu
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 683–685.
https://doi.org/10.1042/EBC20200109
Published: 23 October 2020
View article titled, Guardians of the genome: DNA damage and repair
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Articles

Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane

Matilda Katan, Shamshad Cockcroft
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 513–531.
https://doi.org/10.1042/EBC20200041
Published: 26 August 2020
View article titled, Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane
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Articles

Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease

Emyr Lloyd-Evans, Helen Waller-Evans
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 591–606.
https://doi.org/10.1042/EBC20200043
Published: 05 August 2020
View article titled, Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease
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Articles

The endocannabinoid system

Aruna Kilaru, Kent D. Chapman
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 485–499.
https://doi.org/10.1042/EBC20190086
Published: 10 July 2020
View article titled, The endocannabinoid system
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Articles

Mike Wakelam: an appreciation

Bob Michell
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 397–399.
https://doi.org/10.1042/EBC20200042
Published: 10 July 2020
View article titled, Mike Wakelam: an appreciation
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Articles

Oxidation of polyunsaturated fatty acids to produce lipid mediators

William W. Christie, John L. Harwood
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 401–421.
https://doi.org/10.1042/EBC20190082
Published: 03 July 2020
View article titled, Oxidation of polyunsaturated fatty acids to produce lipid mediators
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Articles

Jasmonates: biosynthesis, perception and signal transduction

Gareth Griffiths
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 501–512.
https://doi.org/10.1042/EBC20190085
Published: 30 June 2020
View article titled, Jasmonates: biosynthesis, perception and signal transduction
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Articles

Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions

Dimitriya H. Garvanska, Jakob Nilsson
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 325–336.
https://doi.org/10.1042/EBC20190065
Published: 05 June 2020
View article titled, Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions
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Articles

Ubiquitin-like proteins in the DNA damage response: the next generation

Isabelle C. Da Costa, Christine K. Schmidt
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 737–752.
https://doi.org/10.1042/EBC20190095
Published: 26 May 2020
View article titled, Ubiquitin-like proteins in the DNA damage response: the next generation
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