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Articles

Polysaccharide sulfotransferases: the identification of putative sequences and respective functional characterisation

Open Access
Ravina Mistry, Dominic P. Byrne, David Starns, Igor L. Barsukov, Edwin A. Yates, David G. Fernig
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (4): 431–447.
https://doi.org/10.1042/EBC20230094
Published: 04 December 2024
View articletitled, Polysaccharide sulfotransferases: the identification of putative sequences and respective functional characterisation
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Articles

Catalytic mechanism and kinetics of malate dehydrogenase

Open Access
Laura de Lorenzo, Tyler M.M. Stack, Kristin M. Fox, Katherine M. Walstrom
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 73–82.
https://doi.org/10.1042/EBC20230086
Published: 03 October 2024
View articletitled, Catalytic mechanism and kinetics of malate dehydrogenase
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Articles

Malate dehydrogenase in plants: evolution, structure, and a myriad of functions

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Lisa M. Baird, Christopher E. Berndsen, Jonathan D. Monroe
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 221–233.
https://doi.org/10.1042/EBC20230089
Published: 03 October 2024
View articletitled, Malate dehydrogenase in plants: evolution, structure, and a myriad of functions
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Articles

The structural biology and dynamics of malate dehydrogenases

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Christopher E. Berndsen, Jessica K. Bell
Journal: Essays in Biochemistry
Essays Biochem (2024) 68 (2): 57–72.
https://doi.org/10.1042/EBC20230082
Published: 03 October 2024
View articletitled, The structural biology and dynamics of malate dehydrogenases
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Includes: Supplementary data
Articles

Oxidoreductases and metal cofactors in the functioning of the earth

Open Access
Bruno Hay Mele, Maria Monticelli, Serena Leone, Deborah Bastoni, Bernardo Barosa, Martina Cascone, Flavia Migliaccio, Francesco Montemagno, Annarita Ricciardelli, Luca Tonietti, Alessandra Rotundi, Angelina Cordone, Donato Giovannelli
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 653–670.
https://doi.org/10.1042/EBC20230012
Published: 11 August 2023
View articletitled, Oxidoreductases and metal cofactors in the functioning of the earth
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Includes: Supplementary data
Articles

Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond!

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Jessica K. Fong, Harry Brumer
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 597–613.
https://doi.org/10.1042/EBC20220124
Published: 18 April 2023
View articletitled, Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond!
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Articles

Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass

Open Access
Johan Larsbrink, Leila Lo Leggio
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 493–503.
https://doi.org/10.1042/EBC20220155
Published: 18 April 2023
View articletitled, Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass
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Articles

Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis

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Víctor Barba-Cedillo, Cédric Y. Montanier
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 629–638.
https://doi.org/10.1042/EBC20220167
Published: 18 April 2023
View articletitled, Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis
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Articles

Glycoside hydrolases active on microbial exopolysaccharide α-glucans: structures and function

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Takatsugu Miyazaki
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 505–520.
https://doi.org/10.1042/EBC20220219
Published: 18 April 2023
View articletitled, Glycoside hydrolases active on microbial exopolysaccharide α-glucans: structures and function
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Articles

Mannuronate C-5 epimerases and their use in alginate modification

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Agnes Beenfeldt Petersen, Anne Tøndervik, Margrethe Gaardløs, Helga Ertesvåg, Håvard Sletta, Finn Lillelund Aachmann
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 615–627.
https://doi.org/10.1042/EBC20220151
Published: 18 April 2023
View articletitled, Mannuronate C-5 epimerases and their use in alginate modification
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Articles

In silico modelling of the function of disease-related CAZymes

Open Access
Alba Nin-Hill, Beatriz Piniello, Carme Rovira
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 355–372.
https://doi.org/10.1042/EBC20220218
Published: 18 April 2023
View articletitled, In silico modelling of the function of disease-related CAZymes
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Articles

Glycosyltransferase family 47 (GT47) proteins in plants and animals

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Liang Zhang, Pradeep Kumar Prabhakar, Vivek S. Bharadwaj, Yannick J. Bomble, Maria J. Peña, Breeanna R. Urbanowicz
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 639–652.
https://doi.org/10.1042/EBC20220152
Published: 14 April 2023
View articletitled, Glycosyltransferase family 47 (GT47) proteins in plants and animals
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Includes: Supplementary data
Articles

Electrospray ion beam deposition plus low-energy electron holography as a tool for imaging individual biomolecules

Open Access
Hannah Ochner, Stephan Rauschenbach, Luigi Malavolti
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 151–163.
https://doi.org/10.1042/EBC20220165
Published: 29 March 2023
View articletitled, Electrospray ion beam deposition plus low-energy electron holography as a tool for imaging individual biomolecules
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Articles

A special issue of Essays in Biochemistry on structural mass spectrometry

Open Access
Hannah M. Britt, Rebecca Beveridge, Antonio N. Calabrese
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 147–149.
https://doi.org/10.1042/EBC20230006
Published: 29 March 2023
View articletitled, A special issue of Essays in Biochemistry on structural mass spectrometry
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Articles

Charge detection mass spectrometry for the analysis of viruses and virus-like particles

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Lohra M. Miller, Martin F. Jarrold
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 315–323.
https://doi.org/10.1042/EBC20220101
Published: 29 March 2023
View articletitled, Charge detection mass spectrometry for the analysis of viruses and virus-like particles
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Articles

Fundamentals of HDX-MS

Open Access
Vanesa Vinciauskaite, Glenn R. Masson
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 301–314.
https://doi.org/10.1042/EBC20220111
Published: 29 March 2023
View articletitled, Fundamentals of HDX-MS
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Articles

Seeing the complete picture: proteins in top-down mass spectrometry

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Tanja Habeck, Frederik Lermyte
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 283–300.
https://doi.org/10.1042/EBC20220098
Published: 29 March 2023
View articletitled, Seeing the complete picture: proteins in top-down mass spectrometry
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Articles

Structural mass spectrometry approaches to understand multidrug efflux systems

Open Access
Benjamin Russell Lewis, Ryan Lawrence, Dietmar Hammerschmid, Eamonn Reading
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 255–267.
https://doi.org/10.1042/EBC20220190
Published: 29 March 2023
View articletitled, Structural mass spectrometry approaches to understand multidrug efflux systems
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Articles

The increasing role of structural proteomics in cyanobacteria

Open Access
Jaspreet K. Sound, Jeddidiah Bellamy-Carter, Aneika C. Leney
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 269–282.
https://doi.org/10.1042/EBC20220095
Published: 29 March 2023
View articletitled, The increasing role of structural proteomics in cyanobacteria
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Articles

Mass spectrometric insights into protein aggregation

Open Access
Tara L. Pukala
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 243–253.
https://doi.org/10.1042/EBC20220103
Published: 29 March 2023
View articletitled, Mass spectrometric insights into protein aggregation
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Articles

Developments in rapid hydrogen–deuterium exchange methods

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Vimanda Chow, Esther Wolf, Cristina Lento, Derek J. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 165–174.
https://doi.org/10.1042/EBC20220174
Published: 29 March 2023
View articletitled, Developments in rapid hydrogen–deuterium exchange methods
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Articles

Cross-linking mass spectrometry for mapping protein complex topologies in situ

Open Access
Kitaik Lee, Francis J. O'Reilly
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 215–228.
https://doi.org/10.1042/EBC20220168
Published: 29 March 2023
View articletitled, Cross-linking mass spectrometry for mapping protein complex topologies in situ
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Articles

Surface-sampling mass spectrometry to study proteins and protein complexes

Open Access
Kei F. Carver Wong, Rebecca E. Greatorex, Charlotte E. Gidman, Sidrah Rahman, Rian L. Griffiths
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 229–241.
https://doi.org/10.1042/EBC20220191
Published: 29 March 2023
View articletitled, Surface-sampling mass spectrometry to study proteins and protein complexes
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Articles

Mass spectrometry of intact membrane proteins: shifting towards a more native-like context

Open Access
Abraham Oluwole, Denis Shutin, Jani R. Bolla
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 201–213.
https://doi.org/10.1042/EBC20220169
Published: 29 March 2023
View articletitled, Mass spectrometry of intact membrane proteins: shifting towards a more native-like context
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Articles

Protein–RNA interactions: from mass spectrometry to drug discovery

Open Access
Benjamin Steinmetz, Izabela Smok, Maria Bikaki, Alexander Leitner
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 175–186.
https://doi.org/10.1042/EBC20220177
Published: 29 March 2023
View articletitled, Protein–RNA interactions: from mass spectrometry to drug discovery
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Articles

Hydrogen/deuterium exchange-mass spectrometry of integral membrane proteins in native-like environments: current scenario and the way forward

Open Access
Waqas Javed, Damon Griffiths, Argyris Politis
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 187–200.
https://doi.org/10.1042/EBC20220173
Published: 29 March 2023
View articletitled, Hydrogen/deuterium exchange-mass spectrometry of integral membrane proteins in native-like environments: current scenario and the way forward
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Articles

Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses

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Frank Gondelaud, Giulia Pesce, Juliet F. Nilsson, Christophe Bignon, Denis Ptchelkine, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 915–934.
https://doi.org/10.1042/EBC20220045
Published: 16 December 2022
View articletitled, Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses
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Includes: Supplementary data
Articles

Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates

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Alexander V. Fonin, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov, Boris Y. Zaslavsky, Prakash Kulkarni, Vladimir N. Uversky
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 831–847.
https://doi.org/10.1042/EBC20220052
Published: 16 December 2022
View articletitled, Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates
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Articles

Different states and the associated fates of biomolecular condensates

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Srivastav Ranganathan, Junlang Liu, Eugene Shakhnovich
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 849–862.
https://doi.org/10.1042/EBC20220054
Published: 16 December 2022
View articletitled, Different states and the associated fates of biomolecular condensates
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Articles

How phosphorylation impacts intrinsically disordered proteins and their function

Open Access
Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann-Petersen, Karen Skriver, Birthe B. Kragelund
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 901–913.
https://doi.org/10.1042/EBC20220060
Published: 16 December 2022
View articletitled, How phosphorylation impacts intrinsically disordered proteins and their function
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Articles

The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer

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Mayra A. Marques, Guilherme A.P. de Oliveira, Jerson L. Silva
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1023–1033.
https://doi.org/10.1042/EBC20220064
Published: 16 December 2022
View articletitled, The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer
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Articles

Shapeshifting tau: from intrinsically disordered to paired-helical filaments

Open Access
Kurtis Mengham, Youssra Al-Hilaly, Sebastian Oakley, Kamillia Kasbi, Mahmoud B. Maina, Louise C. Serpell
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1001–1011.
https://doi.org/10.1042/EBC20220150
Published: 16 December 2022
View articletitled, Shapeshifting tau: from intrinsically disordered to paired-helical filaments
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Articles

How viral proteins bind short linear motifs and intrinsically disordered domains

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Priyanka Madhu, Norman E. Davey, Ylva Ivarsson
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 935–944.
https://doi.org/10.1042/EBC20220047
Published: 16 December 2022
View articletitled, How viral proteins bind short linear motifs and intrinsically disordered domains
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Articles

Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation

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Si Wu, Jitao Wen, Sarah Perrett
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 891–900.
https://doi.org/10.1042/EBC20220148
Published: 16 December 2022
View articletitled, Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation
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Articles

Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease

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Samrat Mukhopadhyay
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 817–819.
https://doi.org/10.1042/EBC20220197
Published: 16 December 2022
View articletitled, Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease
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Articles

Uncovering protein function: from classification to complexes

Open Access
Rhiannon Morris, Katrina A. Black, Elliott J. Stollar
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (3): 255–285.
https://doi.org/10.1042/EBC20200108
Published: 10 August 2022
View articletitled, Uncovering protein function: from classification to complexes
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Articles

Case study: Biochemistry without borders: a case study utilising infographics

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Michelle A. Sahai, Anna Ivanova
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 65–73.
https://doi.org/10.1042/EBC20210040
Published: 29 April 2022
View articletitled, Case study: Biochemistry without borders: a case study utilising infographics
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Articles

Cryo-EM structures of τ filaments from human brain

Open Access
Michel Goedert
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 949–959.
https://doi.org/10.1042/EBC20210025
Published: 22 December 2021
View articletitled, Cryo-EM structures of τ filaments from human brain
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Articles

Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM

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Ping Yi, Xinzhe Yu, Zhao Wang, Bert W. O'Malley
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 857–866.
https://doi.org/10.1042/EBC20210019
Published: 26 November 2021
View articletitled, Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM
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Articles

Ligands and DNA in the allosteric control of retinoid receptors function

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Pierre Germain, Natacha Rochel, William Bourguet
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 887–899.
https://doi.org/10.1042/EBC20200168
Published: 26 November 2021
View articletitled, Ligands and DNA in the allosteric control of retinoid receptors function
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Articles

So you want to express your protein in Escherichia coli ?

Open Access
Aatir A. Tungekar, Angel Castillo-Corujo, Lloyd W. Ruddock
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 247–260.
https://doi.org/10.1042/EBC20200170
Published: 26 July 2021
View articletitled, So you want to express your protein in Escherichia coli ?
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Articles

Label-free, mass-sensitive single-molecule imaging using interferometric scattering microscopy

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Nikolas Hundt
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 81–91.
https://doi.org/10.1042/EBC20200023
Published: 16 April 2021
View articletitled, Label-free, mass-sensitive single-molecule imaging using interferometric scattering microscopy
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Articles

From folding to function: complex macromolecular reactions unraveled one-by-one with optical tweezers

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In Collection
Protein structure and function
Pétur O. Heidarsson, Ciro Cecconi
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 129–142.
https://doi.org/10.1042/EBC20200024
Published: 16 April 2021
View articletitled, From folding to function: complex macromolecular reactions unraveled one-by-one with optical tweezers
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Articles

Integrating single-molecule FRET and biomolecular simulations to study diverse interactions between nucleic acids and proteins

Open Access
Joshua C. Sanders, Erik D. Holmstrom
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 37–49.
https://doi.org/10.1042/EBC20200022
Published: 16 April 2021
View articletitled, Integrating single-molecule FRET and biomolecular simulations to study diverse interactions between nucleic acids and proteins
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Articles

RecQ helicases in DNA repair and cancer targets

Open Access
Joseph A. Newman, Opher Gileadi
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 819–830.
https://doi.org/10.1042/EBC20200012
Published: 23 October 2020
View articletitled, RecQ helicases in DNA repair and cancer targets
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Articles

Uncovering protein structure

Open Access
In Collection
Protein structure and function
Elliott J Stollar, David P Smith
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (4): 649–680.
https://doi.org/10.1042/EBC20190042
Published: 25 September 2020
View articletitled, Uncovering protein structure
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Articles

Structural insight into FANCI–FANCD2 monoubiquitination

Open Access
Landing Li, Winnie Tan, Andrew J. Deans
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 807–817.
https://doi.org/10.1042/EBC20200001
Published: 29 July 2020
View articletitled, Structural insight into FANCI–FANCD2 monoubiquitination
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Articles

CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology

Open Access
Ahmad Ali-Ahmad, Nikolina Sekulić
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 205–221.
https://doi.org/10.1042/EBC20190074
Published: 28 July 2020
View articletitled, CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology
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Articles

Structural view of the yeast Dam1 complex, a ring-shaped molecular coupler for the dynamic microtubule end

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Shaowen Wu, Ekaterina L. Grishchuk
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 359–370.
https://doi.org/10.1042/EBC20190079
Published: 24 June 2020
View articletitled, Structural view of the yeast Dam1 complex, a ring-shaped molecular coupler for the dynamic microtubule end
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Articles

Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining

Open Access
Antonia Kefala Stavridi, Robert Appleby, Shikang Liang, Tom L. Blundell, Amanda K. Chaplin
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 791–806.
https://doi.org/10.1042/EBC20190092
Published: 24 June 2020
View articletitled, Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
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