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Articles

Oxidoreductases and metal cofactors in the functioning of the earth

Bruno Hay Mele, Maria Monticelli, Serena Leone, Deborah Bastoni, Bernardo Barosa, Martina Cascone, Flavia Migliaccio, Francesco Montemagno, Annarita Ricciardelli, Luca Tonietti, Alessandra Rotundi, Angelina Cordone, Donato Giovannelli
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (4): 653–670.
https://doi.org/10.1042/EBC20230012
Published: 11 August 2023
View article titled, Oxidoreductases and metal cofactors in the functioning of the earth
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Includes: Supplementary data
Articles

Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass

Johan Larsbrink, Leila Lo Leggio
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 493–503.
https://doi.org/10.1042/EBC20220155
Published: 18 April 2023
View article titled, Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass
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Articles

Mannuronate C-5 epimerases and their use in alginate modification

Agnes Beenfeldt Petersen, Anne Tøndervik, Margrethe Gaardløs, Helga Ertesvåg, Håvard Sletta, Finn Lillelund Aachmann
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 615–627.
https://doi.org/10.1042/EBC20220151
Published: 18 April 2023
View article titled, Mannuronate C-5 epimerases and their use in alginate modification
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Articles

Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond!

Jessica K. Fong, Harry Brumer
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 597–613.
https://doi.org/10.1042/EBC20220124
Published: 18 April 2023
View article titled, Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond!
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Articles

Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis

Víctor Barba-Cedillo, Cédric Y. Montanier
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 629–638.
https://doi.org/10.1042/EBC20220167
Published: 18 April 2023
View article titled, Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis
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Articles

Glycoside hydrolases active on microbial exopolysaccharide α-glucans: structures and function

Takatsugu Miyazaki
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 505–520.
https://doi.org/10.1042/EBC20220219
Published: 18 April 2023
View article titled, Glycoside hydrolases active on microbial exopolysaccharide α-glucans: structures and function
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Articles

In silico modelling of the function of disease-related CAZymes

Alba Nin-Hill, Beatriz Piniello, Carme Rovira
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 355–372.
https://doi.org/10.1042/EBC20220218
Published: 18 April 2023
View article titled, In silico modelling of the function of disease-related CAZymes
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Articles

Glycosyltransferase family 47 (GT47) proteins in plants and animals

Liang Zhang, Pradeep Kumar Prabhakar, Vivek S. Bharadwaj, Yannick J. Bomble, Maria J. Peña, Breeanna R. Urbanowicz
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 639–652.
https://doi.org/10.1042/EBC20220152
Published: 14 April 2023
View article titled, Glycosyltransferase family 47 (GT47) proteins in plants and animals
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Includes: Supplementary data
Articles

A special issue of Essays in Biochemistry on structural mass spectrometry

Hannah M. Britt, Rebecca Beveridge, Antonio N. Calabrese
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 147–149.
https://doi.org/10.1042/EBC20230006
Published: 29 March 2023
View article titled, A special issue of Essays in Biochemistry on structural mass spectrometry
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Articles

Structural mass spectrometry approaches to understand multidrug efflux systems

Benjamin Russell Lewis, Ryan Lawrence, Dietmar Hammerschmid, Eamonn Reading
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 255–267.
https://doi.org/10.1042/EBC20220190
Published: 29 March 2023
View article titled, Structural mass spectrometry approaches to understand multidrug efflux systems
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Articles

The increasing role of structural proteomics in cyanobacteria

Jaspreet K. Sound, Jeddidiah Bellamy-Carter, Aneika C. Leney
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 269–282.
https://doi.org/10.1042/EBC20220095
Published: 29 March 2023
View article titled, The increasing role of structural proteomics in cyanobacteria
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Articles

Mass spectrometric insights into protein aggregation

Tara L. Pukala
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 243–253.
https://doi.org/10.1042/EBC20220103
Published: 29 March 2023
View article titled, Mass spectrometric insights into protein aggregation
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Articles

Developments in rapid hydrogen–deuterium exchange methods

Vimanda Chow, Esther Wolf, Cristina Lento, Derek J. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 165–174.
https://doi.org/10.1042/EBC20220174
Published: 29 March 2023
View article titled, Developments in rapid hydrogen–deuterium exchange methods
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Articles

Surface-sampling mass spectrometry to study proteins and protein complexes

Kei F. Carver Wong, Rebecca E. Greatorex, Charlotte E. Gidman, Sidrah Rahman, Rian L. Griffiths
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 229–241.
https://doi.org/10.1042/EBC20220191
Published: 29 March 2023
View article titled, Surface-sampling mass spectrometry to study proteins and protein complexes
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Articles

Mass spectrometry of intact membrane proteins: shifting towards a more native-like context

Abraham Oluwole, Denis Shutin, Jani R. Bolla
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 201–213.
https://doi.org/10.1042/EBC20220169
Published: 29 March 2023
View article titled, Mass spectrometry of intact membrane proteins: shifting towards a more native-like context
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Articles

Protein–RNA interactions: from mass spectrometry to drug discovery

Benjamin Steinmetz, Izabela Smok, Maria Bikaki, Alexander Leitner
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 175–186.
https://doi.org/10.1042/EBC20220177
Published: 29 March 2023
View article titled, Protein–RNA interactions: from mass spectrometry to drug discovery
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Articles

Seeing the complete picture: proteins in top-down mass spectrometry

Tanja Habeck, Frederik Lermyte
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 283–300.
https://doi.org/10.1042/EBC20220098
Published: 29 March 2023
View article titled, Seeing the complete picture: proteins in top-down mass spectrometry
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Articles

Cross-linking mass spectrometry for mapping protein complex topologies in situ

Kitaik Lee, Francis J. O'Reilly
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 215–228.
https://doi.org/10.1042/EBC20220168
Published: 29 March 2023
View article titled, Cross-linking mass spectrometry for mapping protein complex topologies in situ
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Articles

Hydrogen/deuterium exchange-mass spectrometry of integral membrane proteins in native-like environments: current scenario and the way forward

Waqas Javed, Damon Griffiths, Argyris Politis
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 187–200.
https://doi.org/10.1042/EBC20220173
Published: 29 March 2023
View article titled, Hydrogen/deuterium exchange-mass spectrometry of integral membrane proteins in native-like environments: current scenario and the way forward
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Articles

Electrospray ion beam deposition plus low-energy electron holography as a tool for imaging individual biomolecules

Hannah Ochner, Stephan Rauschenbach, Luigi Malavolti
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 151–163.
https://doi.org/10.1042/EBC20220165
Published: 29 March 2023
View article titled, Electrospray ion beam deposition plus low-energy electron holography as a tool for imaging individual biomolecules
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Articles

Charge detection mass spectrometry for the analysis of viruses and virus-like particles

Lohra M. Miller, Martin F. Jarrold
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 315–323.
https://doi.org/10.1042/EBC20220101
Published: 29 March 2023
View article titled, Charge detection mass spectrometry for the analysis of viruses and virus-like particles
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Articles

Fundamentals of HDX-MS

Vanesa Vinciauskaite, Glenn R. Masson
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 301–314.
https://doi.org/10.1042/EBC20220111
Published: 29 March 2023
View article titled, Fundamentals of HDX-MS
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Articles

Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease

Samrat Mukhopadhyay
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 817–819.
https://doi.org/10.1042/EBC20220197
Published: 16 December 2022
View article titled, Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease
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Articles

Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses

Frank Gondelaud, Giulia Pesce, Juliet F. Nilsson, Christophe Bignon, Denis Ptchelkine, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 915–934.
https://doi.org/10.1042/EBC20220045
Published: 16 December 2022
View article titled, Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses
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Includes: Supplementary data
Articles

Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates

Alexander V. Fonin, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov, Boris Y. Zaslavsky, Prakash Kulkarni, Vladimir N. Uversky
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 831–847.
https://doi.org/10.1042/EBC20220052
Published: 16 December 2022
View article titled, Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates
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Articles

Different states and the associated fates of biomolecular condensates

Srivastav Ranganathan, Junlang Liu, Eugene Shakhnovich
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 849–862.
https://doi.org/10.1042/EBC20220054
Published: 16 December 2022
View article titled, Different states and the associated fates of biomolecular condensates
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Articles

How phosphorylation impacts intrinsically disordered proteins and their function

Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann-Petersen, Karen Skriver, Birthe B. Kragelund
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 901–913.
https://doi.org/10.1042/EBC20220060
Published: 16 December 2022
View article titled, How phosphorylation impacts intrinsically disordered proteins and their function
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Articles

The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer

Mayra A. Marques, Guilherme A.P. de Oliveira, Jerson L. Silva
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1023–1033.
https://doi.org/10.1042/EBC20220064
Published: 16 December 2022
View article titled, The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer
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Articles

Shapeshifting tau: from intrinsically disordered to paired-helical filaments

Kurtis Mengham, Youssra Al-Hilaly, Sebastian Oakley, Kamillia Kasbi, Mahmoud B. Maina, Louise C. Serpell
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1001–1011.
https://doi.org/10.1042/EBC20220150
Published: 16 December 2022
View article titled, Shapeshifting tau: from intrinsically disordered to paired-helical filaments
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Articles

How viral proteins bind short linear motifs and intrinsically disordered domains

Priyanka Madhu, Norman E. Davey, Ylva Ivarsson
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 935–944.
https://doi.org/10.1042/EBC20220047
Published: 16 December 2022
View article titled, How viral proteins bind short linear motifs and intrinsically disordered domains
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Articles

Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation

Si Wu, Jitao Wen, Sarah Perrett
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 891–900.
https://doi.org/10.1042/EBC20220148
Published: 16 December 2022
View article titled, Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation
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Articles

Uncovering protein function: from classification to complexes

Rhiannon Morris, Katrina A. Black, Elliott J. Stollar
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (3): 255–285.
https://doi.org/10.1042/EBC20200108
Published: 10 August 2022
View article titled, Uncovering protein function: from classification to complexes
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Articles

Case study: Biochemistry without borders: a case study utilising infographics

Michelle A. Sahai, Anna Ivanova
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 65–73.
https://doi.org/10.1042/EBC20210040
Published: 29 April 2022
View article titled, Case study: Biochemistry without borders: a case study utilising infographics
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Articles

Cryo-EM structures of τ filaments from human brain

Michel Goedert
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 949–959.
https://doi.org/10.1042/EBC20210025
Published: 22 December 2021
View article titled, Cryo-EM structures of τ filaments from human brain
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Articles

Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM

Ping Yi, Xinzhe Yu, Zhao Wang, Bert W. O'Malley
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 857–866.
https://doi.org/10.1042/EBC20210019
Published: 26 November 2021
View article titled, Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM
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Articles

Ligands and DNA in the allosteric control of retinoid receptors function

Pierre Germain, Natacha Rochel, William Bourguet
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 887–899.
https://doi.org/10.1042/EBC20200168
Published: 26 November 2021
View article titled, Ligands and DNA in the allosteric control of retinoid receptors function
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Articles

So you want to express your protein in Escherichia coli ?

Aatir A. Tungekar, Angel Castillo-Corujo, Lloyd W. Ruddock
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 247–260.
https://doi.org/10.1042/EBC20200170
Published: 26 July 2021
View article titled, So you want to express your protein in Escherichia coli ?
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Articles

Label-free, mass-sensitive single-molecule imaging using interferometric scattering microscopy

Nikolas Hundt
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 81–91.
https://doi.org/10.1042/EBC20200023
Published: 16 April 2021
View article titled, Label-free, mass-sensitive single-molecule imaging using interferometric scattering microscopy
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Articles

From folding to function: complex macromolecular reactions unraveled one-by-one with optical tweezers

In Collection
Protein structure and function
Pétur O. Heidarsson, Ciro Cecconi
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 129–142.
https://doi.org/10.1042/EBC20200024
Published: 16 April 2021
View article titled, From folding to function: complex macromolecular reactions unraveled one-by-one with optical tweezers
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Articles

Integrating single-molecule FRET and biomolecular simulations to study diverse interactions between nucleic acids and proteins

Joshua C. Sanders, Erik D. Holmstrom
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (1): 37–49.
https://doi.org/10.1042/EBC20200022
Published: 16 April 2021
View article titled, Integrating single-molecule FRET and biomolecular simulations to study diverse interactions between nucleic acids and proteins
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Articles

RecQ helicases in DNA repair and cancer targets

Joseph A. Newman, Opher Gileadi
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 819–830.
https://doi.org/10.1042/EBC20200012
Published: 23 October 2020
View article titled, RecQ helicases in DNA repair and cancer targets
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Articles

Uncovering protein structure

In Collection
Protein structure and function
Elliott J Stollar, David P Smith
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (4): 649–680.
https://doi.org/10.1042/EBC20190042
Published: 25 September 2020
View article titled, Uncovering protein structure
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Articles

Structural insight into FANCI–FANCD2 monoubiquitination

Landing Li, Winnie Tan, Andrew J. Deans
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 807–817.
https://doi.org/10.1042/EBC20200001
Published: 29 July 2020
View article titled, Structural insight into FANCI–FANCD2 monoubiquitination
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Articles

CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology

Ahmad Ali-Ahmad, Nikolina Sekulić
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 205–221.
https://doi.org/10.1042/EBC20190074
Published: 28 July 2020
View article titled, CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology
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Articles

Structural view of the yeast Dam1 complex, a ring-shaped molecular coupler for the dynamic microtubule end

Shaowen Wu, Ekaterina L. Grishchuk
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 359–370.
https://doi.org/10.1042/EBC20190079
Published: 24 June 2020
View article titled, Structural view of the yeast Dam1 complex, a ring-shaped molecular coupler for the dynamic microtubule end
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Articles

Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining

Antonia Kefala Stavridi, Robert Appleby, Shikang Liang, Tom L. Blundell, Amanda K. Chaplin
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 791–806.
https://doi.org/10.1042/EBC20190092
Published: 24 June 2020
View article titled, Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
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Articles

3-Nitrotyrosine and related derivatives in proteins: precursors, radical intermediates and impact in function

Nicolás Campolo, Federico M. Issoglio, Darío A. Estrin, Silvina Bartesaghi, Rafael Radi
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (1): 111–133.
https://doi.org/10.1042/EBC20190052
Published: 04 February 2020
View article titled, 3-Nitrotyrosine and related derivatives in proteins: precursors, radical intermediates and impact in function
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Articles

Collagen-binding proteins: insights from the Collagen Toolkits

Richard W. Farndale
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (3): 337–348.
https://doi.org/10.1042/EBC20180070
Published: 02 July 2019
View article titled, Collagen-binding proteins: insights from the Collagen Toolkits
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Articles

Roles of the procollagen C-propeptides in health and disease

David J.S. Hulmes
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (3): 313–323.
https://doi.org/10.1042/EBC20180049
Published: 26 June 2019
View article titled, Roles of the procollagen C-propeptides in health and disease
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Articles

The nucleosomes that mark centromere location on chromosomes old and new

Craig W. Gambogi, Ben E. Black
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (1): 15–27.
https://doi.org/10.1042/EBC20180060
Published: 23 April 2019
View article titled, The nucleosomes that mark centromere location on chromosomes old and new
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