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Keywords: CENP-A
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Articles
CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology
Open Access
Journal:
Essays in Biochemistry
Essays Biochem (2020) 64 (2): 205–221.
Published: 28 July 2020
...Ahmad Ali-Ahmad; Nikolina Sekulić The centromere is a chromosome locus that directs equal segregation of chromosomes during cell division. A nucleosome containing the histone H3 variant CENP-A epigenetically defines the centromere. Here, we summarize findings from recent structural biology studies...
Articles
Adaptations for centromere function in meiosis
Open Access
Journal:
Essays in Biochemistry
Essays Biochem (2020) 64 (2): 193–203.
Published: 14 May 2020
... of many centromeric proteins. We discuss this observation using the example of the histone variant CENP-A, which marks the centromere and is essential for centromere function. Changes in both the size and the sequence of the CENP-A N-terminal tail have led to additional functions of the protein, which...