..., copy and manipulate DNA sequences alongside a brief consideration of some of the implications for society. Correspondence: Mark A.J. Roberts ( [email protected] ) 02 05 2019 20 08 2019 02 09 2019 © 2019 The Author(s). 2019 This is an open access article published...

... to the escalating challenge of variant interpretation. Thus, integration of functional ‘multi-omics’ data, such as transcriptomics, is emerging as a powerful complementary tool in the diagnosis of mitochondrial disease patients for whom extensive prior analysis of DNA sequencing has failed to return a genetic...