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Keywords: Huntington's disease
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Essays Biochem (2014) 56: 167–180.
Published: 18 August 2014
...Sarah Perrett; Philipp Trepte; Nadine Strempel; Erich E. Wanker PolyQ (polyglutamine) diseases such as HD (Huntington's disease) or SCA1 (spinocerebellar ataxia type 1) are neurodegenerative disorders caused by abnormally elongated polyQ tracts in human proteins. PolyQ expansions promote misfolding...