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Keywords: LC3
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Articles
Essays Biochem (2017) 61 (6): 687–697.
Published: 12 December 2017
... nteraction M otif) in UBA5 [ 40 ], the majority of LIRs contain a core W/F/Y-x 1 -x 2 -L/V/I motif, where the side-chains of the bulky aromatic residue (W/F/Y) are placed deep inside a hydrophobic pocket 1 (HP1) on the Atg8/LC3/GABARAP surface, and side-chains of the hydrophobic LIR residues (L/V/I) occupy...
Articles
Essays Biochem (2013) 55: 51–64.
Published: 27 September 2013
... essential role in autophagosome biogenesis. This family of proteins comprises a single member in yeast and several mammalian homologues grouped into three subfamilies: LC3 (light-chain 3), GABARAP (γ-aminobutyric acid receptor-associated protein) and GATE-16 (Golgi-associated ATPase enhancer of 16 kDa). The...