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Keywords: aging
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Articles
Evo-devo perspectives on cancer
Available to Purchase
Journal:
Essays in Biochemistry
Essays Biochem (2022) 66 (6): 797–815.
Published: 08 December 2022
... ]). For the last several decades, the terms ‘evolution’ and ‘development’ have also been increasingly linked to cancer, in many different frameworks and contexts. aging cancer cancer suppression mechanisms development evolution somatic maintenance “Nothing in cancer makes sense except...
Articles
Alvaro Martinez Guimera, Ciaran Welsh, Piero Dalle Pezze, Nicola Fullard, Glyn Nelson, Mathilde F. Roger, Stefan A. Przyborski, Daryl P. Shanley
Journal:
Essays in Biochemistry
Essays Biochem (2017) 61 (3): 369–377.
Published: 11 July 2017
...Thomas B.L. Kirkwood; Viktor I. Korolchuk; Alvaro Martinez Guimera; Ciaran Welsh; Piero Dalle Pezze; Nicola Fullard; Glyn Nelson; Mathilde F. Roger; Stefan A. Przyborski; Daryl P. Shanley Systems modelling has been successfully used to investigate several key molecular mechanisms of ageing...
Articles
Origins of mtDNA mutations in ageing
Available to Purchase
Journal:
Essays in Biochemistry
Essays Biochem (2017) 61 (3): 325–337.
Published: 11 July 2017
...Thomas B.L. Kirkwood; Viktor I. Korolchuk; Karolina Szczepanowska; Aleksandra Trifunovic MtDNA mutations are one of the hallmarks of ageing and age-related diseases. It is well established that somatic point mutations accumulate in mtDNA of multiple organs and tissues with increasing age...
