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Keywords: aging
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Essays Biochem (2022) 66 (6): 797–815.
Published: 08 December 2022
... or environmentally induced developmental defects, surgery or injury, as well as changes in cell–cell contact during normal processes (including aging) could act as a ‘latent niche’ that can promote the proliferation of competent (stem or pre-cancer) cells in the absence of genetic alterations in either the tumor...
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Essays Biochem (2017) 61 (3): 325–337.
Published: 11 July 2017
...Thomas B.L. Kirkwood; Viktor I. Korolchuk; Karolina Szczepanowska; Aleksandra Trifunovic MtDNA mutations are one of the hallmarks of ageing and age-related diseases. It is well established that somatic point mutations accumulate in mtDNA of multiple organs and tissues with increasing age...