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Keywords: androgens
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Articles
Journal:
Essays in Biochemistry
Essays Biochem (2024) 68 (4): 411–422.
Published: 04 December 2024
... reaction and require 3-phosphoadenosine-5-phosphosulfate as a sulfate donor. These enzymes control the concentration of active estrogens and androgens in peripheral tissues. Aberant expression of STS and SULT genes has been found in both, benign hormone-dependent diseases and hormone-dependent cancers...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2024) 68 (4): 491–507.
Published: 04 December 2024
..., we discuss the importance of steroid enzymes in normal and malignant ovaries, alongside hormone concentrations, receptor expression and action. Key enzymes include STS, 3β-HSD2, HSD17B1, ARK1C3, and aromatase, which influence ovarian steroidal action. Both androgen and oestrogen action, via...
