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Keywords: autophagosome
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Articles
Journal:
Essays in Biochemistry
Essays Biochem (2013) 55: 51–64.
Published: 27 September 2013
...Jon D. Lane; Moran Rawet Slobodkin; Zvulun Elazar Autophagy is an evolutionarily-conserved catabolic process initiated by the engulfment of cytosolic components in a crescent-shaped structure, called the phagophore, that expands and fuses to form a closed double-membrane vesicle, the autophagosome...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2013) 55: 29–38.
Published: 27 September 2013
... that these vesicles, now called autophagosomes, are found in all eukaryotic cells and undergo changes in morphology from a double-membraned vesicle with recognizable content, i.e. sequestered organelles, to a uniformly dense core autolysosome. Genetic screens in the yeast Saccharomyces cerevisiae in the 1990s...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2013) 55: 65–78.
Published: 27 September 2013
... in order to transfer protein and lipid that is needed for them to function. These events must be highly coordinated otherwise non-specific fusion could occur leading to loss of compartment identity and function. The autophagosome is a specialized membrane compartment that delivers cytosolic components...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2013) 55: 133–151.
Published: 27 September 2013
... be addressed to either of these authors ( [email protected] or [email protected] ). © The Authors Journal compilation © 2013 Biochemical Society 2013 anticancer therapy autophagosome chloroquine chronic myeloid leukaemia haemopoietic stem cell hydroxychloroquine...