...James G. Wakefield; Carolyn A. Moores; Kirsty Y. Wan Propulsion by slender cellular appendages called cilia and flagella is an ancient means of locomotion. Unicellular organisms evolved myriad strategies to propel themselves in fluid environments, often involving significant differences in flagella...

...James G. Wakefield; Carolyn A. Moores; Jacob T. Croft; Davide Zabeo; Radhika Subramanian; Johanna L. Höög Cilia and flagella are long extensions commonly found on the surface of eukaryotic cells. In fact, most human cells have a flagellum, and failure to correctly form cilia leads to a spectrum...

...James G. Wakefield; Carolyn A. Moores; Jenna L. Wingfield; Karl-Ferdinand Lechtreck; Esben Lorentzen Bardet–Biedl syndrome (BBS) is a rare inherited disease caused by defects in the BBSome, an octameric complex of BBS proteins. The BBSome is conserved in most organisms with cilia, which...

...Philip Stahl; Graça Raposo; Juan Wang; Maureen M. Barr In this short review, we will focus on the uniqueness of ciliary extracellular vesicles (EVs). In particular, we will review what has been learned regarding EVs produced by cilia of model organisms. Model systems including Chlamydomonas...