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Keywords: epigenome editing
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Articles
Harnessing targeted DNA methylation and demethylation using dCas9
Available to Purchase
Journal:
Essays in Biochemistry
Essays Biochem (2019) 63 (6): 813–825.
Published: 14 November 2019
... to overcome limitations in their efficacy, implementation, and targeting specificity. The concept of targeted epigenome editing generally refers to the recruitment of epigenome modifying proteins (epigenome modifying effectors, or epimodifiers ) to desired genomic loci by tethering them to a locus...