... enhancers located in close proximity, that together do not result in more enhancer activity than the sum of its parts [ 24 , 27 ]. Their precise role needs to be further investigated. To identify putative NCREs, one can take advantage of the several distinct features at different epigenome layers...

... of the Biochemical Society 2019 Figure 3 Summary of targeted DNA methylation editing technologies available Figure created with BioRender.com Correspondence: Ryan Lister ( [email protected] ) 19 09 2019 23 10 2019 24 10 2019 CRISPR epigenetics epigenome...

... and gene loss, generating epigenomic variation both within and between species. They regulate both transposable elements and genes, ensure genome integrity, and ultimately influence development and environmental responses. In these capacities, non-CG methylation influence and shape plant genomes...

... changes in nucleosome array regularity and spacing contribute to the formation of higher order chromatin structures and the spatial organization of the genome in vivo . chromatin epigenomics nucleosomes Most eukaryotes store their nuclear DNA as chromatin, made of repeating units...