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Keywords: estrogen receptors
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Essays Biochem (2021) EBC20200174.
Published: 30 July 2021
...Corinne N. Haines; Suzanne E. Wardell; Donald P. McDonnell Nearly 80% of all breast cancers are estrogen receptor positive (ER+) and require the activity of this transcription factor for tumor growth and survival. Thus, endocrine therapies, which target the estrogen signaling axis, have...