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Keywords: gene expression
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Essays Biochem (2022) 66 (6): 745–752.
Published: 08 December 2022
... regulatory interactions between enhancers and promoters that were once separated into different TADs, which might lead to new gene expression patterns. On the one hand, TAD rearrangements are known to cause deleterious phenotypes, but, on the other hand, rearrangements can also create novel expression...
Essays Biochem (2022) 66 (6): 707–716.
Published: 08 December 2022
... interested in understanding how molecular variation gives rise to phenotypic variation have used three primary strategies to identify the molecular differences underlying species-specific traits: the candidate gene approach, differential gene expression screens, and between-species genetic mapping...
Essays Biochem (2021) 65 (4): 709–721.
Published: 27 October 2021
.... Correspondence: Chung-Chau Hon ( [email protected] ) 22 02 2021 28 07 2021 06 08 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Enhancer Epigenome Gene expression Non-coding RNAs Gene expression is primarily...
Essays Biochem (2018) 62 (4): 535–547.
Published: 12 October 2018
... gene regulation gene expression network reconstruction Inferring regulatory relationships between genes or signalling molecules from perturbation data is one of the big challenges in computational biology. The major problem in disentangling the network structure is that a perturbation...
Includes: Supplementary data