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Keywords: kinase
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Articles
Phosphorylation of mammalian cytosolic and mitochondrial malate dehydrogenase: insights into regulation
Available to PurchaseJoseph J. Provost, Kathleen A Cornely, Pamela S. Mertz, Celeste N. Peterson, Sophie G. Riley, Harrison J. Tarbox, Shree R. Narasimhan, Andrew J Pulido, Amy L. Springer
Journal:
Essays in Biochemistry
Essays Biochem (2024) 68 (2): 183–198.
Published: 03 October 2024
... for the regulatory impact of phosphorylation. We also examine and highlight several approaches to probe the structural and cellular impact of phosphorylation. This review highlights the need to explore the dynamic nature of MDH phosphorylation and calls for identifying the responsible kinases and the physiological...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2022) 66 (5): 621–634.
Published: 30 September 2022
... that is still poorly understood. This review will focus on controls on plant immunity through phosphorylation, a universal and key cellular regulatory mechanism. Rather than a complete overview, we highlight “what’s new in protein kinase/phosphatase signalling” in the immunity field. In addition...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2017) 61 (6): 585–596.
Published: 12 December 2017
... protein kinase ULK1 (unc-51-like kinase 1), which functions in a complex with at least three protein partners: FIP200 (focal adhesion kinase family interacting protein of 200 kDa), ATG (autophagy-related protein) 13 (ATG13), and ATG101. In this artcile, we focus on the regulation of the ULK1 complex...
Articles
Structure-based discovery of cyclin-dependent protein kinase inhibitors
Available to Purchase
Journal:
Essays in Biochemistry
Essays Biochem (2017) 61 (5): 439–452.
Published: 08 November 2017
...Rob L.M. van Montfort; Paul Workman; Mathew P. Martin; Jane A. Endicott; Martin E.M. Noble The cell fate-determining roles played by members of the cyclin-dependent protein kinase (CDK) family explain why their dysregulation can promote proliferative diseases, and identify them as potential targets...
Includes: Supplementary data