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Keywords: molecular mechanisms
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Essays Biochem (2023) 67 (3): 355–372.
Published: 18 April 2023
... molecular dynamics (MD), hybrid quantum mechanics/molecular mechanics (QM/MM), and enhanced sampling techniques) are described for nonexpert readers. Finally, we provide three examples of the application of these methods to unravel the catalytic mechanisms of three disease-related CAZymes: β...
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Essays Biochem (2022) 66 (7): 901–913.
Published: 16 December 2022
... intrinsically disordered proteins molecular mechanisms phosphorylation/dephosphorylation post translational modification protein-protein interactions Intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs, longer than 30 residues) are characterized by their lack of well...
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Essays Biochem (2019) 63 (3): 297–312.
Published: 06 August 2019
... in clinical presentation. collagen extracellular matrix genetics model organisms molecular basis of health and disease molecular mechanisms Basement membranes (BMs) are specialised extracellular matrix (ECM) structures that compartmentalise tissues, provide structural support and influence...
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Essays Biochem (2018) 62 (3): 341–360.
Published: 20 July 2018
...-translational modifications modulating these processes. Understanding the molecular mechanisms controlling mitochondrial dynamics is crucial to decipher how mitochondrial shape meets the function and to increase the knowledge on the molecular basis of diseases associated with morphology defects. This article...
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Essays Biochem (2017) 61 (1): 81–88.
Published: 03 March 2017
... on behalf of the Biochemical Society 2017 antibiotics Clostridium difficile drug resistance molecular mechanisms Clostridium difficile is the leading cause of nosocomial diarrhoea ranging from mild to life-threatening cases and has been attributed to approximately 20% of an antibiotic...