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Keywords: mtDNA mutations
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Essays Biochem (2017) 61 (3): 325–337.
Published: 11 July 2017
...Thomas B.L. Kirkwood; Viktor I. Korolchuk; Karolina Szczepanowska; Aleksandra Trifunovic MtDNA mutations are one of the hallmarks of ageing and age-related diseases. It is well established that somatic point mutations accumulate in mtDNA of multiple organs and tissues with increasing age...