... nuclear receptors structural studies transcription Ligand-dependent nuclear receptors (NRs) are a family of transcription factors that regulate the expression of target genes upon sensing cognate ligands, usually small lipophilic molecules, such as steroid, retinoid, and thyroid hormones...

... College London in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. androgen COVID-19 estrogens nuclear receptors sars-cov-2 steroids The COVID-19 pandemic potentially has a degree of gender bias...

...Sanne C. Lith; Carlie J.M. de Vries Nur77 is a nuclear receptor that has been implicated as a regulator of inflammatory disease. The expression of Nur77 increases upon stimulation of immune cells and is differentially expressed in chronically inflamed organs in human and experimental models...

...Daniel E. Frigo; Maria Bondesson; Cecilia Williams Nuclear receptors are classically defined as ligand-activated transcription factors that regulate key functions in reproduction, development, and physiology. Humans have 48 nuclear receptors, which when dysregulated are often linked to diseases...