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Keywords: p62
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Journal:
Essays in Biochemistry
Essays Biochem (2013) 55: 79–92.
Published: 27 September 2013
... that interact with the human ATG8 orthologues [ 27 ]. An LIR motif alone is not sufficient for recruitment of a protein to the inner surface of the phagophore. Analogous to the oligomerization and aggregation of pre-Ape1 in the Cvt pathway, PB1-domain-mediated polymerization of p62 is absolutely required...