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Keywords: prion-like propagation
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Essays Biochem (2016) 60 (2): 181–190.
Published: 15 October 2016
... affected cells and tissues. In this article, we recap amyloid aggregation pathways, describe prion-like propagation, elaborate on detrimental interactions of protein aggregates with the cellular protein quality control system and discuss why some aggregates are toxic, whereas others seem to be beneficial...