1-8 of 8
Keywords: protein aggregation
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Essays Biochem (2016) 60 (2): 173–180.
Published: 15 October 2016
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution Licence 4.0 (CC BY) . amyloid autophagy chaperone-mediated autophagy immunoglobulin light chain lysosome macroautophagy mTOR Parkinson's disease protein aggregation protein misfolding...
Articles
Essays Biochem (2016) 60 (2): 143–151.
Published: 15 October 2016
... phenotypes and are closely linked with the accumulation of microscopically visible deposits of aggregated proteins. These include inclusion bodies found in AD (Alzheimer's disease), HD (Huntington's disease) and ALS (amyotrophic lateral sclerosis) patient neurons. Protein aggregation is intimately linked...
Articles
Essays Biochem (2016) 60 (2): 163–172.
Published: 15 October 2016
... 2016 © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2016 α-crystallin Hsp27 molecular chaperones protein aggregation protein folding regulation of apoptosis regulation of sHsps structure of sHsps substrate binding sHsps (small...
Articles
Essays Biochem (2016) 60 (2): 181–190.
Published: 15 October 2016
... affected cells and tissues. In this article, we recap amyloid aggregation pathways, describe prion-like propagation, elaborate on detrimental interactions of protein aggregates with the cellular protein quality control system and discuss why some aggregates are toxic, whereas others seem to be beneficial...
Articles
Essays Biochem (2014) 56: 53–68.
Published: 18 August 2014
... protein 90) protein aggregation protein folding proteostasis The native state of functional proteins is a delicate, flexible and, in many cases, metastable conformation. Spontaneous folding to this native state was demonstrated in the early 1960s, when denatured proteins were successfully...
Articles
Essays Biochem (2014) 56: 167–180.
Published: 18 August 2014
... chaperone (−)-epigallocatechin gallate (EGCG) Huntington's disease inclusion body nucleation-dependent polymerization polyglutamine disease protein aggregation PolyQ (polyglutamine) tracts with lengths of between five and 30 glutamine residues are conserved and found in 0.34% of all human...
Articles
Essays Biochem (2014) 56: 149–165.
Published: 18 August 2014
... therapeutics. 1 To whom correspondence should be addressed (email meiering@uwaterloo.ca ). © The Authors Journal compilation © 2014 Biochemical Society 2014 amyotrophic lateral sclerosis (ALS) Cu,Zn superoxide dismutase (SOD1) misfolding protein aggregation protein stability ALS...
Articles
Essays Biochem (2013) 55: 119–131.
Published: 27 September 2013
... are associated with increased cellular stress and assault including DNA damage, reduced energy availability, protein aggregation and accumulation of damaged organelles. A reduction in autophagy activity has been observed in a number of ageing models and its up-regulation via pharmacological and...