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Keywords: secondary metabolite
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Articles

Something old, something new: challenges and developments in Aspergillus niger biotechnology

Open Access
Timothy C. Cairns, Lars Barthel, Vera Meyer
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 213–224.
https://doi.org/10.1042/EBC20200139
Published: 26 July 2021
...Timothy C. Cairns; Lars Barthel; Vera Meyer The filamentous ascomycete fungus Aspergillus niger is a prolific secretor of organic acids, proteins, enzymes and secondary metabolites. Throughout the last century, biotechnologists have developed A. niger into a multipurpose cell factory with a product...
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Articles

The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes

Available to Purchase
Christopher M. Whitford, Pablo Cruz-Morales, Jay D. Keasling, Tilmann Weber
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (2): 261–275.
https://doi.org/10.1042/EBC20200132
Published: 26 July 2021
... Limited on behalf of the Biochemical Society 2021 DBTL metabolic engineering secondary metabolite specialized metabolite Streptomyces Streptomyces are ubiquitous Gram-positive bacteria that produce a broad diversity of specialized metabolites (also referred to as natural products...
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