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Keywords: synapses
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Essays Biochem (2023) 67 (1): 119–130.
Published: 03 March 2023
... and contribute to defects in neurotransmission. The opening of P2X 7 R channels allows calcium influx which modulates the release of glutamate to the synaptic cleft, where it could bind to NMDA-Rs at the post-synapse. P2X 7 R could also participate in the regulation of inhibitory synapses, by modulating...
Essays Biochem (2023) 67 (1): 93–106.
Published: 03 March 2023
...Matthew G. Holt Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess many individual processes which extend out into the neuropil, where they interact with a variety of other cell types, including neurons at synapses. Astrocytes are now known to be active players...
Essays Biochem (2022) 66 (6): 781–795.
Published: 08 December 2022
... and complexity, with neurons possibly representing the most diverse cell-type. This diversity has led to much debate over the evolutionary origin of neurons as well as synapses, which allow for the directed transmission of information. The broad phylogenetic distribution of neurons and presence of many...