..., physical, or biological modification of the surface of probiotics, it is possible to alter their composition and structural display to enhance their chemotaxis and colonization at inflammation sites in the intestines [ 22 ]. Synthetic biology involves the design and construction of biological systems...

... base for a microbial cell factory excelling in synthetic biology applications where evolution meets rational engineering. Correspondence: Suvi Santala ( [email protected] ) 26 01 2021 23 02 2021 25 02 2021 © 2021 The Author(s). Published by Portland Press Limited...

... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . genetic engineering industrial biotechnology metabolic engineering physiology synthetic biology Vibrio natriegens Currently, most...

...Jian-Wen Ye; Guo-Qiang Chen With the rapid development of systems and synthetic biology, the non-model bacteria, Halomonas spp., have been developed recently to become a cost-competitive platform for producing a variety of products including polyesters, chemicals and proteins owing...

... and synthetic biology have broadened the horizon of heterologous protein production using multiple expression platforms. Selection of a suitable expression system depends on a variety of factors ranging from the physicochemical properties of the target protein to economic considerations. For more than 40 years...

... of metabolites by metabolic engineering. A well-annotated genome sequence [ 2 ] as well as genome-editing tools and collections of synthetic biology parts and devices make P. pastoris a promising chassis for synthetic biology applications [ 3 ]. The first yeast strain of what is known today...

... production are summarized. Further, the recent progress in employing metabolic engineering and synthetic biology strategies in B. subtilis platform strain to produce commodity chemicals is systematically introduced and compared. Finally, the major limitations for the further development of B. subtilis...

... extremolytes metabolic engineering plant phenols synthetic biology terpenoids 14 03 2021 26 04 2021 27 04 2021 Corynebacterium glutamicum is a Gram-positive, non-spore-forming facultative anaerobic bacterium with a moderate to high GC content belonging to the phylum...

...Pablo I. Nikel; Diethard Mattanovich An increasingly large number of microbial species with potential for synthetic biology and metabolic engineering has been introduced over the last few years, adding huge variety to the opportunities of biotechnology. Historically, however, only a handful...

... editing epigenomics methyltransferases synthetic biology The complex repertoire of covalent modifications of DNA and histones that adorn the genome have fascinated researchers for decades. Significant advances in profiling the epigenome by genomics technologies have delivered insights...

...Vitor B. Pinheiro; Phil Macnaghten; Richard Owen; Roland Jackson In this article we provide a short review of the debate on responsible innovation and its intersection with synthetic biology, focusing on initiatives we have witnessed and been involved with in the UK. First, we describe the ways...

... desirable functions for bioindustry, such as improved genome stability, increased transformation efficacy and improved production of biomaterials. The minimal genome as a chassis genome for synthetic biology can be used to construct custom-designed genomes for various practical and industrial applications...

... in order to better contend with complex input data. Finally, we compare recent ethical concerns in the field of artificial intelligence (AI) and the future challenges raised by bio-artificial intelligence (BI). artificial intelligence gene networks synthetic biological circuits synthetic biology...

.... Synthetic biology aims to make the engineering of biology easier, offering an opportunity to control natural systems and develop new synthetic systems with useful prescribed behaviours. However, in many cases, it is not understood how individual cells should be programmed to ensure the emergence...