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Keyword: trafficking
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Essays Biochem (2019) 63 (5): 553-567.
Published: 24 September 2019
... signalling cascades to co-ordinate global cellular processes. Syndecans are microenvironment sensors that regulate GTPases to control receptor trafficking, cytoskeletal remodelling and adhesion dynamics. However, an array of crosstalk mechanisms exists, which co-ordinate and integrate the functions of the...
Essays Biochem (2019) 63 (5): 607-618.
Published: 16 August 2019
... feedback loops that serve to initiate and maintain neutrophil polarisation. This is followed by a discussion of recent developments in the understanding of in vivo neutrophil chemotaxis, a process that is frequently referred to as ‘recruitment’ or ‘trafficking’. Here, we summarise neutrophil mobilisation...
Essays Biochem (2018) 62 (2): 215-223.
Published: 15 May 2018
... hedgehog Signalling trafficking Wnt proteins Cell-to-cell communication during development is essential for the organization of tissues and organs. Signalling morphogens are molecules produced in a restricted group of cells and distributed in a graded manner amongst neighbouring cells to promote...
Essays Biochem (2018) 62 (2): 165-175.
Published: 01 May 2018
... ( ajv22@cam.ac.uk ) 22 01 2018 26 02 2018 27 02 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 adipocytes extracellular vesicles exosomes metabolism signalling trafficking In multicellular organisms, where...
Essays Biochem (2015) 57: 43-55.
Published: 06 February 2015
... organizing membranes for signal transduction and protein trafficking as well as in modulating the physiochemical properties of membranes. Cholesterol trafficking among organelles is highly dynamic and is mediated by both vesicular and non-vesicular processes. Several proteins have been proposed to mediate...