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Keywords: ubiquitin-like proteinClose
Journal: Essays in Biochemistry
Essays Biochem (2013) 55: 39–50.
Published: 27 September 2013
... named Atg (autophagy-related). Atg proteins include two ubiquitin-like proteins, Atg12 and Atg8 [LC3 (light-chain 3) and GABARAP (γ-aminobutyric acid receptor-associated protein) in mammals]. Sequential reactions by the E1 enzyme Atg7 and the E2 enzyme Atg10 conjugate Atg12 to the lysine residue in Atg5...