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Keywords: whole-cell models
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Articles
Genome-driven cell engineering review: in vivo and in silico metabolic and genome engineering
Open Access
Journal:
Essays in Biochemistry
Essays Biochem (2019) 63 (2): 267–284.
Published: 26 June 2019
...Sophie Landon; Joshua Rees-Garbutt; Lucia Marucci; Claire Grierson Producing ‘designer cells’ with specific functions is potentially feasible in the near future. Recent developments, including whole-cell models, genome design algorithms and gene editing tools, have advanced the possibility...
Articles
Properties of alternative microbial hosts used in synthetic biology: towards the design of a modular chassis
Open AccessJuhyun Kim, Manuel Salvador, Elizabeth Saunders, Jaime González, Claudio Avignone-Rossa, Jose Ignacio Jiménez
Journal:
Essays in Biochemistry
Essays Biochem (2016) 60 (4): 303–313.
Published: 30 November 2016
... regulatory network as well as of the interplay of the host components with the exogenous circuits, and the possibility of developing whole-cell models and tuneable metabolic fluxes that could allow a better distribution of cellular resources (metabolites, ATP, nucleotides, amino acids, transcriptional...