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Issues
June 2018
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Cover Image
Cover Image
Advances in our understanding of the kappa opioid receptor, including the determination of its structure in complex with the selective antagonist JDTic (main image), have helped pave the way to novel antagonists such as BU10119, a novel analogue of buprenorphine (structures bottom left). In this issue of Neuronal Signalling, Bailey and Husbands discuss the potential of targeting multiple opioid receptors with multifunctional ligands in the treatment of depression. Image created using Forge modeling software (Cresset Biomolecular Discovery Ltd) and Publisher.
EISSN 2059-6553
In this Issue
Review Article
Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?
Neuronal Signal (2018) 2 (2): NS20170145.