A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome
Sarah E. Hurst; Erika Liktor-Busa; Aubin Moutal; Sara Parker; Sydney Rice; Szabolcs Szelinger; Grant Senner; Michael F. Hammer; Laurel Johnstone; Keri Ramsey; Vinodh Narayanan; Samantha Perez-Miller; May Khanna; Heather Dahlin; Karen Lewis; David Craig; Edith H. Wang; Rajesh Khanna; Mark A. Nelson
Neuronal Signal (2018) 2 (3): NS20180141.
Cover ImageThe amygdala of a juvenile rat that has undergone fear extinction. By using double retrograde injections into the prefrontal cortex (blue) and the hippocampus (yellow), along with quantifying markers such as c-Fos (red), a better understanding of the neurocircuitry of fear extinction has been obtained. The image shows many double-labelled cells, indicating that after extinction, amygdala neurons that project to the hippocampus or the prefrontal cortex exhibit c-Fos activation. Image kindly provided by Jee Hyun Kim (University of Melbourne, Australia).