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Keywords: leucine rich repeat kinase
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Articles
Modeling Parkinson’s disease in LRRK2 rodents
Open Access
Journal:
Neuronal Signaling
Neuronal Signal (2023) 7 (3): NS20220040.
Published: 16 August 2023
...Chiara Domenicale; Stefano Magnabosco; Michele Morari Mutations in the leucine-rich repeat kinase 2 ( LRRK2 ) gene are associated with familial and sporadic forms of Parkinson’s disease (PD). Sporadic PD and LRRK2 PD share main clinical and neuropathological features, namely hypokinesia...
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Protein structure and function
Journal:
Neuronal Signaling
Neuronal Signal (2018) 2 (4): NS20180005.
Published: 10 October 2018
...Miho Araki; Genta Ito; Taisuke Tomita Leucine-rich repeat kinase 2 (LRRK2) encodes a 2527-amino acid (aa) protein composed of multiple functional domains, including a Ras of complex proteins (ROC)-type GTP-binding domain, a carboxyl terminal of ROC (COR) domain, a serine/threonine protein kinase...
